8OHM
 
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7MIE
 | | Crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP | | 分子名称: | 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, ... | | 著者 | Davies, C, Singh, A. | | 登録日 | 2021-04-16 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain.
Pathog Dis, 79, 2021
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2X07
 | | cytochrome c peroxidase: engineered ascorbate binding site | | 分子名称: | Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Murphy, E.J, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E. | | 登録日 | 2009-12-07 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase.
Biochemistry, 47, 2008
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7B3Q
 | | Crystal structure of c-MET bound by compound 1 | | 分子名称: | 1-(phenylmethyl)-5~{H}-pyrrolo[3,2-c]pyridin-4-one, Hepatocyte growth factor receptor, SULFATE ION | | 著者 | Collie, G.W. | | 登録日 | 2020-12-01 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis for Targeting the Folded P-Loop Conformation of c-MET.
Acs Med.Chem.Lett., 12, 2021
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7CRG
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4Q9S
 | | Crystal Structure of human Focal Adhesion Kinase (Fak) bound to Compound1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE) | | 分子名称: | 3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1H)-one, Focal adhesion kinase 1 | | 著者 | Argiriadi, M.A, George, D.M. | | 登録日 | 2014-05-01 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Discovery of Selective and Orally Bioavailable Protein Kinase C theta (PKC theta ) Inhibitors from a Fragment Hit.
J.Med.Chem., 58, 2015
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5FGB
 | | Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC33.4 | | 分子名称: | Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, GLYCEROL, ... | | 著者 | Girard-Blanc, C, Rey, F.A, Krey, T. | | 登録日 | 2015-12-20 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus.
J.Virol., 90, 2016
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4WJY
 | | Esherichia coli nitrite reductase NrfA H264N | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cytochrome c-552, ... | | 著者 | Clarke, T.A, Edwards, M.J, Lockwood, C.W.J. | | 登録日 | 2014-10-01 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Resolution of key roles for the distal pocket histidine in cytochrome C nitrite reductases.
J.Am.Chem.Soc., 137, 2015
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4XXL
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6FU3
 | | Structure of the mixed-valence, active form, of cytochrome c peroxidase from obligate human pathogenic bacterium Neisseria gonorrhoeae | | 分子名称: | CALCIUM ION, HEME C, Protein CcpR | | 著者 | Carvalho, A.L, Romao, M.J, Pauleta, S, Nobrega, C. | | 登録日 | 2018-02-26 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the mixed-valence, active form, of cytochrome c peroxidase from obligate human pathogenic bacterium Neisseria gonorrhoeae
To Be Published
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6DO4
 | | KLHDC2 ubiquitin ligase in complex with SelS C-end degron | | 分子名称: | Kelch domain-containing protein 2, SELS C-END DEGRON | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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6DO3
 | | KLHDC2 ubiquitin ligase in complex with SelK C-end degron | | 分子名称: | Kelch domain-containing protein 2, SelK C-end Degron | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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2XRU
 | | AURORA-A T288E COMPLEXED WITH PHA-828300 | | 分子名称: | 3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMINO)-N-[(1R)-1-PHENYLPROPYL]-1H-THIENO[3,2-C]PYRAZOLE-5-CARBOXAMIDE, SERINE/THREONINE-PROTEIN KINASE 6 | | 著者 | Bindi, S, Fancelli, D, Alli, C, Berta, D, Bertrand, J.A, Cameron, A.D, Cappella, P, Carpinelli, P, Cervi, G, Croci, W, D'Anello, M, Forte, B, LauraGiorgini, M, Marsiglio, A, Moll, J, Pesenti, E, Pittala, V, Pulici, M, Riccardi-Sirtori, F, Roletto, F, Soncini, C, Storici, P, Varasi, M, Volpi, D, Zugnoni, P, Vianello, P. | | 登録日 | 2010-09-22 | | 公開日 | 2010-09-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Thieno[3,2-C]Pyrazoles: A Novel Class of Aurora Inhibitors with Favorable Antitumor Activity.
Bioorg.Med.Chem., 18, 2010
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1PKG
 | | Structure of a c-Kit Kinase Product Complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, c-kit protein | | 著者 | Mol, C.D, Lim, K.B, Sridhar, V, Zou, H, Chien, E.Y.T, Sang, B.-C, Nowakowski, J, Kassel, D.B, Cronin, C.N, McRee, D.E. | | 登録日 | 2003-06-05 | | 公開日 | 2003-08-12 | | 最終更新日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation.
J.Biol.Chem., 278, 2003
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5FGC
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5D9A
 | | Influenza C Virus RNA-dependent RNA Polymerase - Space group P212121 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | | 著者 | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | | 登録日 | 2015-08-18 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Nature, 527, 2015
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5D98
 | | Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212 | | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | | 登録日 | 2015-08-18 | | 公開日 | 2015-10-21 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Nature, 527, 2015
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1O0E
 | | 1.9 Angstrom Crystal Structure of a plant cysteine protease Ervatamin C | | 分子名称: | Ervatamin C, THIOSULFATE | | 著者 | Thakurta, P.G, Chakrabarti, C, Biswas, S, Dattagupta, J.K. | | 登録日 | 2003-02-21 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis of the Unusual Stability and Substrate Specificity of Ervatamin C, a Plant Cysteine Protease from Ervatamia coronaria
Biochemistry, 43, 2004
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3I04
 | | Cyanide-bound structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica, cyanide-bound C-cluster | | 分子名称: | ACETATE ION, COPPER (I) ION, CYANIDE ION, ... | | 著者 | Kung, Y, Doukov, T.I, Drennan, C.L. | | 登録日 | 2009-06-24 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Biochemistry, 48, 2009
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3LKH
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3OUE
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2VR0
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6I7Q
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1NML
 | | Di-haemic Cytochrome c Peroxidase from Pseudomonas nautica 617, form IN (pH 4.0) | | 分子名称: | CITRIC ACID, HEME C, di-haem cytochrome c peroxidase | | 著者 | Dias, J.M, Bonifacio, C, Alves, T, Pereira, A.S, Bourgeois, D, Moura, I, Romao, M.J. | | 登録日 | 2003-01-10 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the mechanism of Ca(2+) activation of the di-heme cytochrome c peroxidase from Pseudomonas nautica 617
Structure, 12, 2004
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6CAM
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