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5DGE
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Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-27
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
4V6P
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Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-12-08
公開日2014-07-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V71
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V4Y
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BU of 4v4y by Molmil
Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated Shine-Dalgarno Duplex.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
登録日2006-06-27
公開日2014-07-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V89
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Crystal Structure of Release Factor RF3 Trapped in the GTP State on a Rotated Conformation of the Ribosome (without viomycin)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhou, J, Lancaster, L, Trakhanov, S, Noller, H.F.
登録日2011-11-17
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome.
Rna, 18, 2012
4V5C
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BU of 4v5c by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA.
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
登録日2009-03-24
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
4V5R
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BU of 4v5r by Molmil
The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V6G
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BU of 4v6g by Molmil
Initiation complex of 70S ribosome with two tRNAs and mRNA.
分子名称: 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jenner, L.B, Yusupova, G, Yusupov, M.
登録日2009-07-10
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V8M
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BU of 4v8m by Molmil
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ...
著者Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J.
登録日2012-12-09
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.57 Å)
主引用文献High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
4V75
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BU of 4v75 by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic post-translocation state (post1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7J
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BU of 4v7j by Molmil
Structure of RelE nuclease bound to the 70S ribosome (precleavage state)
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
登録日2009-11-02
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
4V84
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BU of 4v84 by Molmil
Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
登録日2010-12-13
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
4V8O
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BU of 4v8o by Molmil
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jin, H, Kelley, A.C, Ramakrishnan, V.
登録日2011-07-26
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal Structure of the Hybrid State of Ribosome in Complex with the Guanosine Triphosphatase Release Factor 3.
Proc.Natl.Acad.Sci.USA, 108, 2011
4V9B
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BU of 4v9b by Molmil
Crystal Structure of the 70S ribosome with tigecycline.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jenner, L, Yusupov, M, Yusupova, G.
登録日2012-07-18
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V8U
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BU of 4v8u by Molmil
Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex.
分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Gao, Y.G, Feng, S, Chen, Y.
登録日2012-08-28
公開日2014-07-09
最終更新日2019-10-30
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex.
PLoS ONE, 8, 2013
4V9M
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BU of 4v9m by Molmil
70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2013-04-25
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
4W29
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BU of 4w29 by Molmil
70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2014-07-02
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation.
Science, 345, 2014
6MPI
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BU of 6mpi by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-10-07
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MKN
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BU of 6mkn by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Cantara, W.A, DeMirci, H, Agris, P.F.
登録日2018-09-25
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MTD
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BU of 6mtd by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel)
分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
著者Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
登録日2018-10-19
公開日2018-11-21
最終更新日2019-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTE
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BU of 6mte by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state)
分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
著者Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
登録日2018-10-19
公開日2018-11-21
最終更新日2019-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6N1D
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BU of 6n1d by Molmil
X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric Hybrid State
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Noller, H.F, Donohue, J.P, Lancaster, L, Zhou, J.
登録日2018-11-08
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Spontaneous ribosomal translocation of mRNA and tRNAs into a chimeric hybrid state.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N9F
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BU of 6n9f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ...
著者Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S.
登録日2018-12-03
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
6N9E
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BU of 6n9e by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ...
著者Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S.
登録日2018-12-03
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
6NDK
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BU of 6ndk by Molmil
Structure of ASLSufA6 A37.5 bound to the 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.T, Hoffer, E.D, Dunham, C.M.
登録日2018-12-13
公開日2019-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing intRNACGGProfor decoding
J. Biol. Chem., 294, 2019

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