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8X64
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CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with desloratadine
分子名称: Histamine H1 receptor,Soluble cytochrome b562, desloratadine
著者Wang, D.D, Guo, Q.
登録日2023-11-20
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8X63
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CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine
分子名称: Histamine H1 receptor,Soluble cytochrome b562, mepyramine
著者Wang, D.D, Guo, Q.
登録日2023-11-20
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8X5Y
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CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with astemizole
分子名称: 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Histamine H1 receptor,Soluble cytochrome b562
著者Wang, D.D, Guo, Q, Tao, Y.Y.
登録日2023-11-20
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
7X6O
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Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12
分子名称: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of antibody 12 fab
著者Cong, Y, Liu, C.X.
登録日2022-03-07
公開日2022-03-23
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.
Nat Commun, 13, 2022
7MEM
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BU of 7mem by Molmil
CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ...
著者Han, J, Ward, A.
登録日2021-04-06
公開日2021-07-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes.
Sci Transl Med, 13, 2021
2LHP
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High resolution NMR solution structure of helix H1 of the chimpanzee HAR1 RNA
分子名称: RNA (37-MER)
著者Cevec, M, Ziegeler, M, Richter, C, Schwalbe, H.
登録日2011-08-12
公開日2012-07-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Studies of HAR1 RNA Secondary Structures Reveal Conformational Dynamics in the Human RNA.
Chembiochem, 13, 2012
6DPI
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 K196A in Complex with an RNA/DNA Hybrid: Reaction in 10 mM Mg2+ and 200 mM Rb+ for 40 s at 21 C
分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.347 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DPN
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C
分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.493 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
5IBL
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Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6639 Heavy Chain, 6639 Light Chain, ...
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
7T3D
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CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ...
著者Han, J, Ward, A.B.
登録日2021-12-07
公開日2022-01-12
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Nature, 602, 2022
4EDA
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Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I.
登録日2012-03-27
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Insight into structural diversity of influenza virus haemagglutinin
J.Gen.Virol., 94, 2013
4EDB
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BU of 4edb by Molmil
Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses
分子名称: Hemagglutinin
著者Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I.
登録日2012-03-27
公開日2013-05-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into structural diversity of influenza virus haemagglutinin
J.Gen.Virol., 94, 2013
7DFL
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BU of 7dfl by Molmil
Cryo-EM structure of histamine H1 receptor Gq complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ...
著者He, Y, Xia, R, Wang, N, Xu, Z.
登録日2020-11-09
公開日2021-03-31
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the human histamine H 1 receptor/G q complex.
Nat Commun, 12, 2021
4OJO
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Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Lactose
分子名称: Tailspike protein, ZINC ION, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
著者Chen, C, Herzberg, O.
登録日2014-01-21
公開日2014-03-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein.
Plos One, 9, 2014
4OJP
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Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Maltose
分子名称: Tailspike protein, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Chen, C, Herzberg, O.
登録日2014-01-21
公開日2014-03-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein.
Plos One, 9, 2014
4OJL
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Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Glucose
分子名称: Tailspike protein, ZINC ION, beta-D-glucopyranose
著者Chen, C, Herzberg, O.
登録日2014-01-21
公開日2014-03-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein.
Plos One, 9, 2014
3ZTN
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STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY LIGHT CHAIN, ...
著者Hubbard, P.A, Ritchie, A.J, Corti, D, Voss, J.E, Gamblin, S.J, Codoni, G, Macagno, A, Jarrossay, D, Pinna, D, Minola, A, Vanzetta, F, Silacci, C, Fernandez-Rodriguez, B.M, Agatic, G, Giacchetto-Sasselli, I, Vachieri, S.G, Sallusto, F, Collins, P.J, Haire, L.F, Temperton, N, Langedijk, J.P.M, Skehel, J.J, Lanzavecchia, A.
登録日2011-07-12
公開日2011-08-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
4OJ5
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Crystal Structure of a Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120
分子名称: Tailspike protein, ZINC ION
著者Chen, C, Herzberg, O.
登録日2014-01-20
公開日2014-03-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein.
Plos One, 9, 2014
4A01
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BU of 4a01 by Molmil
Crystal Structure of the H-Translocating Pyrophosphatase
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, IMIDODIPHOSPHORIC ACID, MAGNESIUM ION, ...
著者Lin, S.-M, Tsai, J.-Y, Hsiao, C.-D, Chiu, C.-L, Pan, R.-L, Sun, Y.-J.
登録日2011-09-07
公開日2012-03-28
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure of a Membrane Embedded H1-Translocating Pyrophosphatase
Nature, 484, 2012
5GJT
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Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ...
著者Wang, W, Zhang, T, Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5GJS
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Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Wang, W, Zhang, T, Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
4RSY
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Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, ACETIC ACID, IMIDAZOLE, ...
著者Ouyang, P, Lu, W, Cui, K, Huang, J.
登録日2014-11-12
公開日2015-12-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
To be Published
6I19
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Crystal structure of Chlamydomonas reinhardtii thioredoxin h1
分子名称: Thioredoxin H-type
著者Lemaire, S.D, Tedesco, D, Crozet, P, Michelet, L, Fermani, S, Zaffagnini, M, Henri, J.
登録日2018-10-27
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.378 Å)
主引用文献Crystal Structure of Chloroplastic Thioredoxin f2 fromChlamydomonas reinhardtiiReveals Distinct Surface Properties.
Antioxidants (Basel), 7, 2018
5VMF
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Influenza hemagglutinin H1 mutant DH1D in complex with 6'SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Ni, F, Kondrashkina, E, Wang, Q.
登録日2017-04-27
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Determinant of receptor-preference switch in influenza hemagglutinin.
Virology, 513, 2017
5VMJ
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Influenza hemagglutinin H1 mutant DH1E in complex with 3'SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Ni, F, Kondrashkina, E, Wang, Q.
登録日2017-04-27
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Determinant of receptor-preference switch in influenza hemagglutinin.
Virology, 513, 2017

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件を2024-08-14に公開中

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