8X63

CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine

Summary for 8X63

• Entry DOI: 10.2210/pdb8x63/pdb
• EMDB information: 38078
• Descriptor: Histamine H1 receptor,Soluble cytochrome b562, mepyramine (2 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 50914.75

Authors

Wang, D.D.,Guo, Q. (deposition date: 2023-11-20, release date: 2024-01-17)

• Primary citation: Wang, D.,Guo, Q.,Wu, Z.,Li, M.,He, B.,Du, Y.,Zhang, K.,Tao, Y.; Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.; Nat Commun, 15:84-84, 2024; PubMed: 38167898; DOI: 10.1038/s41467-023-44477-4

Experimental method

ELECTRON MICROSCOPY (3.2 Å)