PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4EUC	Succinyl-CoA:acetate CoA-transferase (AarCH6-E294A) in complex with dethiaacetyl-CoA 分子名称: CHLORIDE ION, Succinyl-CoA:acetate coenzyme A transferase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(4-oxidanylidenepentylamino)propyl]amino]butyl] hydrogen phosphate 著者 Mullins, E.A, Kappock, T.J. 登録日 2012-04-25 公開日 2012-10-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.644 Å) 主引用文献 Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
4N62	Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... 著者 Xu, R, Wilson, I.A. 登録日 2013-10-11 公開日 2013-12-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5026 Å) 主引用文献 Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013
7W2P	Tudor domain of SMN in complex with a small molecule 分子名称: 2-[(4-fluorophenyl)methyl]-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),3(7)-dien-8-imine, MAGNESIUM ION, Survival motor neuron protein, ... 著者 Li, W, Arrowsmith, C.H, Edwards, A.M, Liu, Y, Min, J. 登録日 2021-11-24 公開日 2022-10-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
7W30	Tudor domain of SMN in complex with a small molecule 分子名称: 1,2-dimethylquinolin-4-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION 著者 Li, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Liu, Y, Min, J. 登録日 2021-11-24 公開日 2022-10-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
3J3Z	Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment 分子名称: MA28-7 neutralizing antibody heavy chain, MA28-7 neutralizing antibody light chain 著者 Lee, H, Cifuente, J.O, Ashley, R.E, Conway, J.F, Makhov, A.M, Tano, Y, Shimizu, H, Nishimura, Y, Hafenstein, S. 登録日 2013-05-21 公開日 2013-08-28 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (23.4 Å) 主引用文献 A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody. J.Virol., 87, 2013
5O3H	Human Brd2(BD2) mutant in complex with 9-ME-Am1 分子名称: (2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-9-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-~{N}-ethyl-propanamide, (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
5ODE	Structure of a novel oxidoreductase from Gloeobacter violaceus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Gll2934 protein, SULFATE ION 著者 Buey, R.M, Galindo-Trigo, S, de Pereda, J.M, Balsera, M. 登録日 2017-07-05 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.196 Å) 主引用文献 Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4MZL	Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic 分子名称: Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic 著者 Douse, C.H, Garnett, J.A, Maas, S.J, Cota, E, Tate, E.W. 登録日 2013-09-30 公開日 2013-11-06 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction. Acs Chem.Biol., 8, 2014
4C3P	Structure of dephosphorylated Aurora A (122-403) bound to TPX2 and AMPPCP 分子名称: AURORA KINASE A, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION, ... 著者 Zorba, A, Kutter, S, Kern, D. 登録日 2013-08-26 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Molecular Mechanism of Aurora a Kinase Autophosphorylation and its Allosteric Activation by Tpx2. Elife, 3, 2014
4C3R	Structure of dephosphorylated Aurora A (122-403) bound to AMPPCP 分子名称: AURORA KINASE A, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Zorba, A, Kutter, S, Cho, Y.-J, Kern, D. 登録日 2013-08-26 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Molecular Mechanism of Aurora a Kinase Autophosphorylation and its Allosteric Activation by Tpx2. Elife, 3, 2014
4NZU	Crystal structure of the primary monoclonal antibody 13PL Fab' from a multiple myeloma patient 分子名称: 13PL heavy chain, 13PL light chain, ACETATE ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2013-12-12 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science, 343, 2014
3GEF	Crystal structure of the R482W mutant of lamin A/C 分子名称: Lamin-A/C 著者 Magracheva, E, Kozlov, S, Stuart, C, Wlodawer, A, Zdanov, A. 登録日 2009-02-25 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD). Acta Crystallogr.,Sect.F, 65, 2009
1Z9J	Photosynthetic Reaction Center from Rhodobacter sphaeroides 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... 著者 Thielges, M, Uyeda, G, Camara-Artigas, A, Kalman, L, Williams, J.C, Allen, J.P. 登録日 2005-04-02 公開日 2005-06-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Design of a Redox-Linked Active Metal Site: Manganese Bound to Bacterial Reaction Centers at a Site Resembling That of Photosystem II Biochemistry, 44, 2005
6KDX	Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor 分子名称: MAGNESIUM ION, N-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]quinolin-2-amine, ZINC ION, ... 著者 Amano, Y, Honbou, K. 登録日 2019-07-03 公開日 2019-08-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. Bioorg.Med.Chem., 27, 2019
3E7V	Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand 分子名称: 1,2-ETHANEDIOL, 3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine, NICKEL (II) ION, ... 著者 Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2008-08-19 公開日 2008-10-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand To be Published
1N59	Crystal structure of the Murine class I Major Histocompatibility Complex of H-2KB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... 著者 Achour, A, Michaelsson, J, Harris, R.A, Odeberg, J, Grufman, P, Sandberg, J.K, Levitsky, V, Karre, K, Sandalova, T, Schneider, G. 登録日 2002-11-05 公開日 2003-01-07 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 A Structural Basis for LCMV Immune Evasion. Subversion of H-2D(b) and H-2K(b) Presentation of gp33 Revealed by Comparative Crystal Structure Analyses. Immunity, 17, 2002
1N5A	Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Achour, A, Michaelsson, J, Harris, R.A, Odeberg, J, Grufman, P, Sandberg, J.K, Levitsky, V, Karre, K, Sandalova, T, Schneider, G. 登録日 2002-11-05 公開日 2003-01-07 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A Structural Basis for LCMV Immune Evasion. Subversion of H-2D(b) and H-2K(b) Presentation of gp33 Revealed by Comparative Crystal Structure Analyses. Immunity, 17, 2002
4CPB	CRYSTAL STRUCTURE OF LECA IN COMPLEX WITH A DIVALENT GALACTOSIDE AT 1. 57 ANGSTROM IN MAGNESIUM 分子名称: (4S)-N-ethyl-4-{[N-methyl-3-(1-{2-[(4-sulfanylbenzoyl)amino]ethyl}-1H-1,2,3-triazol-4-yl)-L-alanyl]amino}-L-prolinamide, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Topin, J, Varrot, A, Imberty, A, Wissinger, N. 登録日 2014-02-04 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A Leca Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion by Pseudomonas Aeruginosa. Angew.Chem.Int.Ed.Engl., 53, 2014
1KH8	Structure of a cis-proline (P114) to glycine variant of Ribonuclease A 分子名称: CESIUM ION, SULFATE ION, pancreatic ribonuclease A 著者 Schultz, D.A, Friedman, A.M, White, M.A, Fox, R.O. 登録日 2001-11-29 公開日 2003-06-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A. Protein Sci., 14, 2005
4H6U	Tubulin acetyltransferase mutant 分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION, ... 著者 Roll-Mecak, A, Kizub, V, Szyk, A. 登録日 2012-09-19 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4482 Å) 主引用文献 Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus. J.Biol.Chem., 287, 2012
4C9I	Crystal Structure of the Strawberry Pathogenesis-Related 10 (PR-10) Fra a 1E protein (Form B) 分子名称: (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, GLYCEROL, MAJOR STRAWBERRY ALLERGEN FRA A 1-E 著者 Casanal, A, Zander, U, Valpuesta, V, Marquez, J.A. 登録日 2013-10-02 公開日 2013-10-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Strawberry Pathogenesis-Related 10 (Pr-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates. J.Biol.Chem., 288, 2013
4H6Z	Tubulin acetyltransferase 分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION 著者 Kizub, L, Szyk, A, Piszczek, G, Roll-Mecak, A. 登録日 2012-09-19 公開日 2012-11-07 最終更新日 2012-12-26 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus. J.Biol.Chem., 287, 2012
6KDZ	Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor 分子名称: 4-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]-3,7,8,10-tetrazatricyclo[7.4.0.0^{2,7}]trideca-1,3,5,8,10,12-hexaen-6-ol, MAGNESIUM ION, ZINC ION, ... 著者 Amano, Y, Honbou, K. 登録日 2019-07-03 公開日 2019-08-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. Bioorg.Med.Chem., 27, 2019
4IJL	Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A 分子名称: Replication protein A 70 kDa DNA-binding subunit, {[5-(3-chloro-1-benzothiophen-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid 著者 Feldkamp, M.D, Patrone, J.D, Kennedy, J.P, Frank, A.O, Vangamudi, B, Pelz, N.F, Rossanese, O.W, Waterson, A.G, Fesik, S.W, Chazin, W.J. 登録日 2012-12-21 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. ACS MED.CHEM.LETT., 4, 2013
3H2K	Crystal structure of a ligand-bound form of the rice cell wall degrading esterase LipA from Xanthomonas oryzae 分子名称: esterase, octyl beta-D-glucopyranoside 著者 Aparna, G, Chatterjee, A, Sonti, R.V, Sankaranarayanan, R. 登録日 2009-04-14 公開日 2009-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Cell Wall-Degrading Esterase of Xanthomonas oryzae Requires a Unique Substrate Recognition Module for Pathogenesis on Rice Plant Cell, 21, 2009

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