4MZL

Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic

Summary for 4MZL

Entry DOI	10.2210/pdb4mzl/pdb
Related	4AOM 4MZJ 4MZK
Related PRD ID	PRD_001188
Descriptor	Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic (3 entities in total)
Functional Keywords	actomyosin motor, stapled peptides, protein binding-inhibitor complex, alpha-helix mimetic, protein binding/inhibitor
Biological source	Plasmodium falciparum 3D7 More
Cellular location	Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : 4MZL
Total number of polymer chains	4
Total formula weight	37157.59
Authors	Douse, C.H.,Garnett, J.A.,Maas, S.J.,Cota, E.,Tate, E.W. (deposition date: 2013-09-30, release date: 2013-11-06, Last modification date: 2023-06-07)
Primary citation	Douse, C.H.,Maas, S.J.,Thomas, J.C.,Garnett, J.A.,Sun, Y.,Cota, E.,Tate, E.W. Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction. Acs Chem.Biol., 8:506-512, 2014 Cited by PubMed: 25084543 DOI: 10.1021/cb500271c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation