4C3R
Structure of dephosphorylated Aurora A (122-403) bound to AMPPCP
Summary for 4C3R
Entry DOI | 10.2210/pdb4c3r/pdb |
Related | 4C3P |
Descriptor | AURORA KINASE A, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER (2 entities in total) |
Functional Keywords | transferase, aurora a, activation, cell cycle, cancer |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 33194.67 |
Authors | Zorba, A.,Kutter, S.,Cho, Y.-J.,Kern, D. (deposition date: 2013-08-26, release date: 2014-05-28, Last modification date: 2023-12-20) |
Primary citation | Zorba, A.,Buosi, V.,Kutter, S.,Kern, N.,Pontiggia, F.,Cho, Y.J.,Kern, D. Molecular Mechanism of Aurora a Kinase Autophosphorylation and its Allosteric Activation by Tpx2. Elife, 3:02667-, 2014 Cited by PubMed: 24867643DOI: 10.7554/ELIFE.02667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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