PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

---

6XTE	Human karyopherin RanBP5 (isoform-1) 分子名称: Antipain, CHLORIDE ION, Importin-5, ... 著者 Swale, C, McCarthy, A.A, Ruigrok, R.W.H, Crepin, T. 登録日 2020-01-16 公開日 2020-04-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
8J9A	Solution structure of ABD3 (residues 453-561) of human MED15 isoform 2 分子名称: Mediator of RNA polymerase II transcription subunit 15 著者 Zhang, H, Li, Y. 登録日 2023-05-03 公開日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution structure of ABD3 (residues 453-561) of human MED15 isoform 2 To Be Published
6B3E	Crystal structure of human CDK12/CyclinK in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, 2-[(2S)-1-(6-{[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]amino}-9-ethyl-9H-purin-2-yl)piperidin-2-yl]ethan-1-ol, Cyclin-K, ... 著者 Ferguson, A.D. 登録日 2017-09-21 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structure-Based Design of Selective Noncovalent CDK12 Inhibitors. ChemMedChem, 13, 2018
6XU2	Human karyopherin RanBP5 (isoform-3) 分子名称: Antipain, Importin-5, NICKEL (II) ION 著者 Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T. 登録日 2020-01-17 公開日 2020-04-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.834 Å) 主引用文献 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
4BY6	Yeast Not1-Not2-Not5 complex 分子名称: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Bhaskar, V, Basquin, J, Conti, E. 登録日 2013-07-18 公開日 2013-10-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structure and RNA-Binding Properties of the not1-not2-not5 Module of the Yeast Ccr4-not Complex Nat.Struct.Mol.Biol., 20, 2013
2B5I	cytokine receptor complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common gamma chain, ... 著者 Wang, X, Rickert, M, Garcia, K.C. 登録日 2005-09-28 公開日 2005-11-29 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science, 310, 2005
6EUX	Structure of the midlink and cap-binding domains of influenza B polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor 分子名称: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2 著者 Cusack, S, Gaudon, S. 登録日 2017-10-31 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
1U49	Adenine-8oxoguanine mismatch at the polymerase active site 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
2IVX	Crystal structure of human cyclin T2 at 1.8 A resolution 分子名称: 1,2-ETHANEDIOL, CYCLIN-T2 著者 Debreczeni, J.E, Bullock, A.N, Fedorov, O, Savitsky, P, Berridge, G, Das, S, Pike, A.C.W, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Gorrec, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. 登録日 2006-06-21 公開日 2006-07-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation. EMBO J., 27, 2008
8Q1N	Cyclic peptide binder of the WBM-site of WDR5 分子名称: Cyclic peptide inhibitor, WD repeat-containing protein 5 著者 Schmeing, S, Chang, J.Y, t Hart, P, Gasper, R. 登録日 2023-08-01 公開日 2023-09-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.843 Å) 主引用文献 Macrocyclic peptides as inhibitors of WDR5-lncRNA interactions. Chem.Commun.(Camb.), 59, 2023
4P2G	Crystal structure of DJ-1 in sulfinic acid form (aged crystal) 分子名称: 1,2-ETHANEDIOL, PENTAETHYLENE GLYCOL, Protein DJ-1 著者 Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. 登録日 2014-03-04 公開日 2014-04-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
5HVY	CDK8/CYCC IN COMPLEX WITH COMPOUND 20 分子名称: CHLORIDE ION, Cyclin-C, Cyclin-dependent kinase 8, ... 著者 Kiefer, J.R, Schneider, E.V, Maskos, K, Bergeron, P, Koehler, M. 登録日 2016-01-28 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8. Acs Med.Chem.Lett., 7, 2016
6E3N	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-4-oxo-6-(o-tolyl)-1,4-dihydropyridine-2-carboxylic acid 分子名称: 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E3O	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid 分子名称: 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E3P	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-(1H-tetrazol-5-yl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid 分子名称: 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
4P34	Crystal structure of DJ-1 in sulfenic acid form (fresh crystal) 分子名称: PENTAETHYLENE GLYCOL, Protein DJ-1 著者 Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. 登録日 2014-03-05 公開日 2014-04-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
6WBV	Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc 分子名称: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, COBALT (II) ION, Fab45D8 Heavy Chain, ... 著者 Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. 登録日 2020-03-27 公開日 2020-09-09 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms. Nature, 586, 2020
3SQ4	RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (GC rich sequence) 分子名称: 5'-D(*CP*GP*CP*GP*CP*GP*GP*CP*GP*GP*CP*GP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*CP*GP*CP*CP*GP*CP*CP*GP*CP*GP*CP*GP*G)-3', CALCIUM ION, ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-04 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
4OR5	Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... 著者 Gu, J, Babayeva, N.D, Suwa, Y, Baranovskiy, A.G, Price, D.H, Tahirov, T.H. 登録日 2014-02-10 公開日 2014-04-16 最終更新日 2014-06-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13, 2014
4FC8	Crystal structure of transcription regulator protein Rtr1 from Kluyveromyces lactis 分子名称: ZINC ION, transcription protein Rtr1 著者 Xiang, K, Tong, L. 登録日 2012-05-24 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity. Nat Commun, 3, 2012
3SQ2	RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (AT rich sequence) 分子名称: 5'-D(*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*G)-3', CALCIUM ION, ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-04 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
4N4G	Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha 分子名称: PHOSPHATE ION, ZINC ION, Zinc finger MYND domain-containing protein 11 著者 Li, Y, Ren, Y, Li, H. 登録日 2013-10-08 公開日 2014-03-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.947 Å) 主引用文献 ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
6QP0	Crystal structure of Chaetomium thermophilum Kti12 in complex with ADP-AlF3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... 著者 Krutyholowa, R, Glatt, S. 登録日 2019-02-13 公開日 2019-03-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator. Nucleic Acids Res., 47, 2019
1MNM	YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE 分子名称: DNA (STE6 OPERATOR DNA), PROTEIN (MAT ALPHA-2 TRANSCRIPTIONAL REPRESSOR), PROTEIN (MCM1 TRANSCRIPTIONAL REGULATOR) 著者 Tan, S, Richmond, T.J. 登録日 1997-11-03 公開日 1998-03-18 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex. Nature, 391, 1998
2BZ2	Solution structure of NELF E RRM 分子名称: NEGATIVE ELONGATION FACTOR E 著者 Schweimer, K, Rao, J.N, Neumann, L, Rosch, P, Wohrl, B.M. 登録日 2005-08-10 公開日 2006-08-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural studies on the RNA-recognition motif of NELF E, a cellular negative transcription elongation factor involved in the regulation of HIV transcription. Biochem. J., 400, 2006

<71727374757677787980818283848586>