4OR5
Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4
Summary for 4OR5
Entry DOI | 10.2210/pdb4or5/pdb |
Descriptor | Cyclin-dependent kinase 9, Cyclin-T1, Protein Tat, ... (8 entities in total) |
Functional Keywords | cdk9, tat, aff4, zinc finger, transcription, rna binding, phosphorylation, transferase-transcription complex, transferase/transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P50750 O60563 Q9UHB7 Host nucleus, host nucleolus: P04608 |
Total number of polymer chains | 8 |
Total formula weight | 159543.94 |
Authors | Gu, J.,Babayeva, N.D.,Suwa, Y.,Baranovskiy, A.G.,Price, D.H.,Tahirov, T.H. (deposition date: 2014-02-10, release date: 2014-04-16, Last modification date: 2014-06-11) |
Primary citation | Gu, J.,Babayeva, N.D.,Suwa, Y.,Baranovskiy, A.G.,Price, D.H.,Tahirov, T.H. Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13:1788-1797, 2014 Cited by PubMed: 24727379DOI: 10.4161/cc.28756 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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