PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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6ROY	Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif 分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM) 著者 Krausze, J, Sikorska, J, Carlomagno, T. 登録日 2019-05-13 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular mechanism of SHP2 activation by PD-1 stimulation. Sci Adv, 6, 2020
6TWR	Structure of a constitutively active CAT-PRD1 mutant of the antiterminator LicT protein. 分子名称: Beta-glucoside bgl operon antiterminator BglG family 著者 Demene, H, Declerck, N, Yinshan, Y. 登録日 2020-01-13 公開日 2021-04-14 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Resolving the activation mechanism of the D99N antiterminator LicT protein. J.Struct.Biol., 213, 2021
5L2R	Crystal structure of fumarate hydratase from Leishmania major 分子名称: (2S)-2-hydroxybutanedioic acid, DI(HYDROXYETHYL)ETHER, Fumarate hydratase, ... 著者 Feliciano, P.R, Drennan, C.L, Nonato, M.C. 登録日 2016-08-02 公開日 2016-08-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.054 Å) 主引用文献 Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from Leishmania major reveals a unique protein fold. Proc.Natl.Acad.Sci.USA, 113, 2016
6MC3	Crystal structure of a tetrameric DNA fold-back quadruplex 分子名称: DNA (5'-D(*CP*GP*TP*GP*AP*GP*GP*CP*G)-3'), MAGNESIUM ION 著者 Chu, B, Paukstelis, P.J. 登録日 2018-08-30 公開日 2018-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystal Structure of a Tetrameric DNA Fold-Back Quadruplex. J. Am. Chem. Soc., 140, 2018
8A9J	Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323 (consensus reconstruction) 分子名称: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... 著者 Rennie, M.L, Walden, H. 登録日 2022-06-28 公開日 2022-10-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
2JLP	Crystal structure of human extracellular copper-zinc superoxide dismutase. 分子名称: COPPER (II) ION, EXTRACELLULAR SUPEROXIDE DISMUTASE (CU-ZN), THIOCYANATE ION, ... 著者 Antonyuk, S.V, Strange, R.W, Marklund, S.L, Hasnain, S.S. 登録日 2008-09-14 公開日 2009-03-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding. J.Mol.Biol., 388, 2009
7ZH3	USP1 bound to ubiquitin conjugated to FANCD2 (focused refinement) 分子名称: Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ZINC ION 著者 Rennie, M.L, Walden, H. 登録日 2022-04-05 公開日 2022-10-12 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
8PZQ	Model for focused reconstruction of influenza A RNP-like particle 分子名称: Nucleoprotein, RNA (5'P-(UC)6-FAM3') 著者 Chenavier, F, Estrozi, L.F, Zarkadas, E, Ruigrok, R.W.H, Schoehn, G, Ballandras-Colas, A, Crepin, T. 登録日 2023-07-27 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv, 9, 2023
6RSQ	Helical folded domain of mouse CAP1 分子名称: Adenylyl cyclase-associated protein 1, GLYCEROL 著者 Kotila, T, Kogan, K, Lappalainen, P. 登録日 2019-05-22 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat Commun, 10, 2019
6AC5	Crystal structure of RIPK1 death domain GlcNAcylated by EPEC effector NleB 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-interacting serine/threonine-protein kinase 1, SULFATE ION 著者 Ding, J, Shao, F. 登録日 2018-07-25 公開日 2019-05-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector. Mol.Cell, 74, 2019
6MG4	Structure of full-length human lambda-6A light chain JTO 分子名称: JTO light chain 著者 Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W. 登録日 2018-09-12 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Stabilization of amyloidogenic immunoglobulin light chains by small molecules. Proc.Natl.Acad.Sci.USA, 116, 2019
5IKF	Crystal structure of the C-terminal domain of the Mit1 nucleosome remodeler in complex with Clr1 分子名称: CHLORIDE ION, Chromatin remodeling factor mit1, Cryptic loci regulator protein 1, ... 著者 Brugger, C, Schalch, T. 登録日 2016-03-03 公開日 2016-04-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules. Mol.Cell, 62, 2016
5IIV	GCN4p pH 1.5 分子名称: General control protein GCN4 著者 Brady, M.R, Kaplan, A.R, Alexandrescu, A.T. 登録日 2016-03-01 公開日 2017-03-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix. Biochemistry, 56, 2017
6LKE	in meso full-length rat KMO in complex with an inhibitor identified via DNA-encoded chemical library screening 分子名称: 4-chloranyl-2-[[5-chloranyl-2-(5-methoxy-1,3-dihydroisoindol-2-yl)-1,3-thiazol-4-yl]carbonyl-methyl-amino]-5-fluoranyl-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Mimasu, S, Yamagishi, H, Kiyohara, M, Hupp, D.C, Liu, J, Kakefuda, K, Okuda, T. 登録日 2019-12-19 公開日 2020-12-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4, 2021
6AHY	Wnt signaling complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Hirai, H, Arimori, T, Matoba, K, Mihara, E, Takagi, J. 登録日 2018-08-21 公開日 2019-05-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of a mammalian Wnt-frizzled complex. Nat.Struct.Mol.Biol., 26, 2019
5L0J	Human vinculin R903Q, D907R, R910T mutant(residues 891-1066) 分子名称: Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
8G2Y	Cryo-EM structure of ADGRF1 coupled to miniGs/q 分子名称: Adhesion G-protein-coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Jones, D, Rawson, S, Blacklow, S. 登録日 2023-02-06 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.44 Å) 主引用文献 Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nat Commun, 14, 2023
7JMN	Tail module of Mediator complex 分子名称: MED15, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 16, ... 著者 Zhang, H.Q, Chen, D.C. 登録日 2020-08-02 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Mediator structure and conformation change. Mol.Cell, 81, 2021
6AHG	Trimeric structure of concanavalin A from Canavalia ensiformis 分子名称: CADMIUM ION, CALCIUM ION, Concanavalin-A,Concanavalin-A 著者 Park, J.H, Kim, D.S, Park, Y.R, Lee, S.J. 登録日 2018-08-18 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Cadmium-substituted concanavalin A and its trimeric complexation J. Microbiol. Biotechnol., 28(12), 2018
8PZP	Model for influenza A virus helical ribonucleoprotein-like structure 分子名称: Nucleoprotein, RNA (5'P-(UC)6-FAM3') 著者 Chenavier, F, Estrozi, L.F, Zarkadas, E, Ruigrok, R.W.H, Schoehn, G, Ballandras-Colas, A, Crepin, T. 登録日 2023-07-27 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv, 9, 2023
6UTN	Native E. coli Glyceraldehyde 3-phosphate dehydrogenase 分子名称: ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, PHOSPHATE ION, ... 著者 Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. 登録日 2019-10-29 公開日 2019-12-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion Crystals, 9, 2019
6S5D	Square conformation of KtrA R16A mutant ring with bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, MAGNESIUM ION 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-01 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.393 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
6S5G	Non-square conformation of KtrA A80P mutant ring with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-01 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.33 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
8FOI	Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with GABA and allopregnanolone 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, DODECANE, ... 著者 Sun, C, Gouaux, E. 登録日 2022-12-30 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
6LT7	Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncRNA RMRP 分子名称: 1,2-ETHANEDIOL, 50-mer RNA, Ribonuclease P protein subunit p20, ... 著者 Huang, J, Yin, C. 登録日 2020-01-21 公開日 2021-01-27 最終更新日 2021-04-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncRNA RMRP. J.Struct.Biol., 213, 2021

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