6LKE

in meso full-length rat KMO in complex with an inhibitor identified via DNA-encoded chemical library screening

Summary for 6LKE

• Entry DOI: 10.2210/pdb6lke/pdb
• Descriptor: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... (6 entities in total)
• Functional Keywords: single-pass transmembrane proteins, kmo, fad, flavoprotein, membrane protein
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 2
• Total formula weight: 115665.27

Authors

Mimasu, S.,Yamagishi, H.,Kiyohara, M.,Hupp, D.C.,Liu, J.,Kakefuda, K.,Okuda, T. (deposition date: 2019-12-19, release date: 2020-12-23, Last modification date: 2023-11-22)

• Primary citation: Mimasu, S.,Yamagishi, H.,Kubo, S.,Kiyohara, M.,Matsuda, T.,Yahata, T.,Thomson, H.A.,Hupp, C.D.,Liu, J.,Okuda, T.,Kakefuda, K.; Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.; Commun Biol, 4:159-159, 2021; PubMed: 33542467; DOI: 10.1038/s42003-021-01666-5

Experimental method

X-RAY DIFFRACTION (3 Å)