PDB: 35415 件ウェブページステータス検索Chemie searchBIRD

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4PVD	Crystal structure of yeast methylglyoxal/isovaleraldehyde reductase Gre2 complexed with NADPH 分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent methylglyoxal reductase GRE2 著者 Guo, P.C, Bao, Z.Z, Li, W.F, Zhou, C.Z. 登録日 2014-03-17 公開日 2014-10-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2 Biochim.Biophys.Acta, 1844, 2014
7ZU6	Polyoxidovanadate interaction with proteins: crystal structure of lysozyme bound to tetra-vanadate ion (structure 1) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CYCLO-TETRAMETAVANADATE, Lysozyme, ... 著者 Tito, G, Merlino, A, Ferraro, G. 登録日 2022-05-11 公開日 2023-05-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.183 Å) 主引用文献 Stabilization and Binding of [V 4 O 12 ] 4- and Unprecedented [V 20 O 54 (NO 3 )] n- to Lysozyme upon Loss of Ligands and Oxidation of the Potential Drug V IV O(acetylacetonato) 2. Angew.Chem.Int.Ed.Engl., 62, 2023
1ASZ	THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER) 著者 Cavarelli, J, Rees, B, Thierry, J.C, Moras, D. 登録日 1995-01-19 公開日 1995-05-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. EMBO J., 13, 1994
4PWV	Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain 分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, Peptide synthetase, ... 著者 Haslinger, K, Cryle, M.J. 登録日 2014-03-21 公開日 2014-07-23 最終更新日 2014-08-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of a transient complex of a nonribosomal Peptide synthetase and a cytochrome p450 monooxygenase. Angew.Chem.Int.Ed.Engl., 53, 2014
4PXE	The crystal structure of AtUAH in complex with glyoxylate 分子名称: GLYOXYLIC ACID, MANGANESE (II) ION, Ureidoglycolate hydrolase 著者 Shin, I, Rhee, S. 登録日 2014-03-23 公開日 2014-07-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.449 Å) 主引用文献 Structural insights into the substrate specificity of (s)-ureidoglycolate amidohydrolase and its comparison with allantoate amidohydrolase. J.Mol.Biol., 426, 2014
6B9T	Crystal structure of MPnS with substrate 2-hydroxyethylphosphonate (2-HEP) and Fe(II) bound 分子名称: (2-hydroxyethyl)phosphonic acid, FE (III) ION, FORMIC ACID, ... 著者 Born, D.A, Drennan, C.L. 登録日 2017-10-11 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for methylphosphonate biosynthesis. Science, 358, 2017
1AO6	CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN 分子名称: SERUM ALBUMIN 著者 Sugio, S, Mochizuki, S, Noda, M, Kashima, A. 登録日 1997-07-18 公開日 1998-05-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human serum albumin at 2.5 A resolution. Protein Eng., 12, 1999
5LWO	Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K 分子名称: 2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. 登録日 2016-09-18 公開日 2017-03-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.183 Å) 主引用文献 Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins. J Phys Chem Lett, 8, 2017
5LTE	Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) 分子名称: 2-ETHOXYETHANOL, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... 著者 Ortmayer, M, Leys, D. 登録日 2016-09-06 公開日 2016-11-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme. Nature, 539, 2016
5LUM	Alpha-crystallin domain of human HSPB6 patched with its N-terminal peptide 分子名称: Heat shock protein beta-6, SULFATE ION 著者 Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. 登録日 2016-09-09 公開日 2017-02-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator. Structure, 25, 2017
5LUS	Structures of DHBN domain of Pelecanus crispus BLM helicase 分子名称: BLM helicase 著者 Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. 登録日 2016-09-09 公開日 2017-03-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.433 Å) 主引用文献 A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
1IJ8	CRYSTAL STRUCTURE OF LITE AVIDIN-BNI COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, AVIDIN 著者 Livnah, O, Huberman, T. 登録日 2001-04-25 公開日 2001-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chicken avidin exhibits pseudo-catalytic properties. Biochemical, structural, and electrostatic consequences. J.Biol.Chem., 276, 2001
7ZWA	CryoEM structure of Ku heterodimer bound to DNA and PAXX 分子名称: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ... 著者 Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. 登録日 2022-05-19 公開日 2023-05-31 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8DCS	Cryo-EM structure of cyanopindolol-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein 分子名称: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Su, M, Paknejad, N, Hite, R.K, Huang, X.Y. 登録日 2022-06-17 公開日 2022-07-27 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies. Nat Commun, 13, 2022
7ZLT	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Snee, M, Kavanagh, M, Levy, C. 登録日 2022-04-15 公開日 2023-05-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor To Be Published
6B5H	ALDH1A2 liganded with NAD and 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121) 分子名称: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2 著者 Chen, Y, Zhu, J.-Y, Schonbrunn, E. 登録日 2017-09-29 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors. ACS Chem. Biol., 13, 2018
3WE4	Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole 分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, Ribosomal protein S6 kinase beta-1, ZINC ION 著者 Niwa, H, Shirouzu, M, Yokoyama, S. 登録日 2013-06-29 公開日 2014-08-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.995 Å) 主引用文献 Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
4Q3S	Crystal structure of Schistosoma mansoni arginase in complex with inhibitor ABHPE 分子名称: Arginase, GLYCEROL, MANGANESE (II) ION, ... 著者 Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. 登録日 2014-04-12 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
5LDR	Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain in complex with galactose 分子名称: ACETATE ION, Beta-D-galactosidase, CHLORIDE ION, ... 著者 Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G. 登録日 2016-06-27 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d. Acta Crystallogr D Struct Biol, 72, 2016
3WTM	Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Nitromethylene Analogue of Imidacloprid 分子名称: 2-chloro-5-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}pyridine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
6B6L	The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ... 著者 Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2017-10-02 公開日 2017-10-11 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 To Be Published
8A9Q	Computational design of stable mammalian serum albumins for bacterial expression 分子名称: Albumin, LAURIC ACID, MYRISTIC ACID, ... 著者 Khersonsky, O, Dym, O, Fleishman, J.S. 登録日 2022-06-29 公開日 2023-05-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Stable Mammalian Serum Albumins Designed for Bacterial Expression. J.Mol.Biol., 435, 2023
5LZU	Structure of the mammalian ribosomal termination complex with accommodated eRF1 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5M1Z	STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR 分子名称: 1,2-ETHANEDIOL, Exo-1,5-alpha-L-arabinofuranobiosidase, GLYCEROL, ... 著者 Varrot, A. 登録日 2016-10-11 公開日 2016-12-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploiting sp(2) -Hybridisation in the Development of Potent 1,5-alpha-l-Arabinanase Inhibitors. Chembiochem, 18, 2017
8DCR	Cryo-EM structure of dobutamine-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein 分子名称: DOBUTAMINE, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Su, M, Paknejad, N, Hite, R.K, Huang, X.Y. 登録日 2022-06-17 公開日 2022-07-27 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies. Nat Commun, 13, 2022

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