4PVD
Crystal structure of yeast methylglyoxal/isovaleraldehyde reductase Gre2 complexed with NADPH
Summary for 4PVD
Entry DOI | 10.2210/pdb4pvd/pdb |
Related | 4PVC |
Descriptor | NADPH-dependent methylglyoxal reductase GRE2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | rossmann fold, reductase, nadph binding, oxidoreductase |
Biological source | Saccharomyces cerevisiae (yeast) |
Cellular location | Cytoplasm : Q12068 |
Total number of polymer chains | 4 |
Total formula weight | 154372.58 |
Authors | Guo, P.C.,Bao, Z.Z.,Li, W.F.,Zhou, C.Z. (deposition date: 2014-03-17, release date: 2014-10-22, Last modification date: 2023-11-08) |
Primary citation | Guo, P.C.,Bao, Z.Z.,Ma, X.X.,Xia, Q.,Li, W.F. Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2 Biochim.Biophys.Acta, 1844:1486-1492, 2014 Cited by PubMed: 24879127DOI: 10.1016/j.bbapap.2014.05.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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