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3T29
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BU of 3t29 by Molmil
TMAO-grown trigonal trypsin (bovine)
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者Cahn, J, Venkat, M, Marshall, H, Juers, D.
登録日2011-07-22
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
3T2J
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BU of 3t2j by Molmil
Tetragonal thermolysin in the presence of betaine
分子名称: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Cahn, J, Hti Lar Seng, N.S, Juers, D.
登録日2011-07-22
公開日2011-12-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
3SZE
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BU of 3sze by Molmil
Crystal structure of the passenger domain of the E. coli autotransporter EspP
分子名称: Serine protease espP
著者Khan, S, Mian, H.S, Sandercock, L.E, Battaile, K.P, Lam, R, Chirgadze, N.Y, Pai, E.F.
登録日2011-07-18
公開日2011-10-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspP.
J.Mol.Biol., 413, 2011
6HD0
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BU of 6hd0 by Molmil
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Plant UBX domain-containing protein 1, Transitional endoplasmic reticulum ATPase
著者Heinemann, U, Roske, Y, Banchenko, S.
登録日2018-08-17
公開日2019-08-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.728 Å)
主引用文献Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1.
Structure, 27, 2019
3T1Y
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BU of 3t1y by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
登録日2011-07-22
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
3T3R
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BU of 3t3r by Molmil
Human Cytochrome P450 2A6 in complex with Pilocarpine
分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE
著者DeVore, N.M, Scott, E.E.
登録日2011-07-25
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.
Febs J., 279, 2012
6LU1
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BU of 6lu1 by Molmil
Cyanobacterial PSI Monomer from T. elongatus by Single Particle CRYO-EM at 3.2 A Resolution
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Kurisu, G, Coruh, O, Tanaka, H, Gerle, C, Kawamoto, A, Kato, T, Namba, K, Nowaczyk, M.M, Rogner, M, Misumi, Y, Frank, A, Eithar, E.M.
登録日2020-01-24
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster.
Commun Biol, 4, 2021
6HVU
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Yeast 20S proteasome with human beta2i (1-53) in complex with 29
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2018-10-11
公開日2019-01-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6JPQ
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CryoEM structure of Abo1 hexamer - ADP complex
分子名称: Uncharacterized AAA domain-containing protein C31G5.19
著者Cho, C, Jang, J, Song, J.J.
登録日2019-03-27
公開日2020-08-19
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.44 Å)
主引用文献Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
6JDX
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BU of 6jdx by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin
分子名称: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-02
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6MKS
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BU of 6mks by Molmil
Cryo-EM structure of NLRC4-CARD filament
分子名称: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2018-09-26
公開日2018-11-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
6JMH
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BU of 6jmh by Molmil
Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 Haem Domain with N-Abietoyl-L-Tryptophan
分子名称: (2S)-2-[[(1R,4aR,4bR,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthren-1-yl]carbonylamino]-3-( 1H-indol-3-yl)propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
著者Stanfield, J.K, Omura, K, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y, Shoji, O.
登録日2019-03-10
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Crystals in Minutes: Instant On-Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JMT
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BU of 6jmt by Molmil
Crystal structure of GIT/PIX complex
分子名称: ARF GTPase-activating protein GIT2, ZINC ION, beta PIX
著者Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M.
登録日2019-03-13
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
6MJL
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BU of 6mjl by Molmil
Crystal structure of ChREBP NLS peptide bound to importin alpha.
分子名称: ChREBP Peptide ASN-TYR-TRP-LYS-ARG-ARG-ILE-GLU-VAL, Importin subunit alpha-1
著者Jung, H, Uyeda, K.
登録日2018-09-21
公開日2019-09-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of importin alpha and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin alpha interactions.
Biochem.J., 477, 2020
6MKR
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BU of 6mkr by Molmil
5287 TCR bound to IAb Padi4
分子名称: 5287 TCR alpha chain, 5287 TCR beta chain, H-2 class II histocompatibility antigen, ...
著者Stadinski, B.D, Blevins, S.J, Huseby, E.S.
登録日2018-09-26
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.355 Å)
主引用文献A temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3+Tregcell development.
Nat.Immunol., 20, 2019
6JP5
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BU of 6jp5 by Molmil
Rabbit Cav1.1-Nifedipine Complex
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhao, Y, Huang, G, Wu, J, Yan, N.
登録日2019-03-25
公開日2019-06-12
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel.
Cell, 177, 2019
6MK9
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BU of 6mk9 by Molmil
X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121
分子名称: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease
著者Yedidi, R.S, Hayashi, H, Das, D, Mitsuya, H.
登録日2018-09-25
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121
To Be Published
3S7S
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BU of 3s7s by Molmil
Crystal structure of human placental aromatase complexed with breast cancer drug exemestane
分子名称: (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
著者Ghosh, D.
登録日2011-05-26
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
3S82
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Structure of a S-adenosylmethionine synthetase from Mycobacterium avium
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-05-27
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
6J7I
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BU of 6j7i by Molmil
Fusion protein of heme oxygenase-1 and NADPH cytochrome P450 reductase (15aa)
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ...
著者Sugishima, M, Sato, H, Wada, K, Yamamoto, K.
登録日2019-01-18
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding.
Febs Lett., 593, 2019
3SHF
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Crystal structure of the R265S mutant of full-length murine Apaf-1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Apoptotic peptidase activating factor 1, GAMMA-BUTYROLACTONE
著者Eschenburg, S, Reubold, T.F.
登録日2011-06-16
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis.
Structure, 19, 2011
6GSA
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BU of 6gsa by Molmil
Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10
分子名称: Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Zhang, W.J, Lukoynova, N, Vaughan, C.K.
登録日2018-06-13
公開日2018-08-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
6GTZ
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Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside Man(alpha1-3)Man in space group P21
分子名称: FimG protein, FimH protein, alpha-D-mannopyranose-(1-3)-methyl alpha-D-mannopyranoside
著者Jakob, R.P, Sauer, M.M, Luber, T, Canonica, F, Navarra, G, Ernst, B, Unverzagt, C, Maier, T, Glockshuber, R.
登録日2018-06-19
公開日2019-01-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.719 Å)
主引用文献Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets.
J.Am.Chem.Soc., 141, 2019
6GYP
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Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore
分子名称: ARGININE, ASPARAGINE, Centromere DNA-binding protein complex CBF3 subunit A, ...
著者Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2018-07-01
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
3SYX
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BU of 3syx by Molmil
Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein. Northeast Structural Genomics Consortium Target HR5538B.
分子名称: Sprouty-related, EVH1 domain-containing protein 1, YTTRIUM (III) ION
著者Vorobiev, S, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2011-07-18
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.453 Å)
主引用文献Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein.
To be Published

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件を2024-08-14に公開中

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