3SHF

Crystal structure of the R265S mutant of full-length murine Apaf-1

Summary for 3SHF

Entry DOI	10.2210/pdb3shf/pdb
Related	3sfz
Descriptor	Apoptotic peptidase activating factor 1, ADENOSINE-5'-DIPHOSPHATE, GAMMA-BUTYROLACTONE, ... (4 entities in total)
Functional Keywords	tandem beta-propeller, apoptosis, cytochrome c, adenine nucleotide, procaspase-9, cytosol
Biological source	Mus musculus (mouse)
Total number of polymer chains	1
Total formula weight	142458.61
Authors	Eschenburg, S.,Reubold, T.F. (deposition date: 2011-06-16, release date: 2011-08-24, Last modification date: 2023-09-13)
Primary citation	Reubold, T.F.,Wohlgemuth, S.,Eschenburg, S. Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis. Structure, 19:1074-1083, 2011 Cited by PubMed: 21827944 DOI: 10.1016/j.str.2011.05.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.55 Å)

Structure validation