3SHF
Crystal structure of the R265S mutant of full-length murine Apaf-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Apoptotic peptidase activating factor 1 | polymer | 1256 | 141859.2 | 1 | UniProt (A2RRK8) Pfam (PF00619) Pfam (PF00400) Pfam (PF00931) Pfam (PF21296) Pfam (PF17908) UniProt (by SIFTS) (O88879) | Mus musculus (mouse) | Apaf-1 |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D (A) | GAMMA-BUTYROLACTONE | non-polymer | 86.1 | 2 | Chemie (GBL) | |||
| 4 | E (A) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A: 1 - 1249 (UniProt: A2RRK8)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Met -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Ser 265 | Arg 265 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 141859.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 599.4 | |
| All* | Total formula weight | 142458.6 |
