PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

---

4M9T	NS2B-NS3 protease from dengue virus in the presence of DTNB, a covalent allosteric inhibitor 分子名称: CHLORIDE ION, NS2B-NS3 protease 著者 Bell, J.A, Yildiz, M, Hardy, J.A. 登録日 2013-08-15 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8, 2013
6CLU	Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure 分子名称: Dihydropteroate synthase 著者 Gajewski, S, Griffith, E.C, Wu, Y, White, S.W. 登録日 2018-03-02 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase. Front Microbiol, 9, 2018
6QZI	Crystal structure of human Aquaporin 7 at 1.9 A resolution 分子名称: Aquaporin-7, GLYCEROL, PHOSPHATE ION 著者 de Mare, S.W.-H, Venskutonyte, R, Eltschkner, S, Lindkvist-Petersson, K. 登録日 2019-03-11 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7. Structure, 28, 2020
4LZF	A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal P4.1-associated protein, SCL-interrupting locus protein homolog, ... 著者 Hatzopoulos, G.N, Erat, M.C, Cutts, E, Rogala, K, Slatter, L, Stansfeld, P.J, Vakonakis, I. 登録日 2013-07-31 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure, 21, 2013
6CBA	Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and canavanine 分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L-CANAVANINE, ... 著者 Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. 登録日 2018-02-02 公開日 2019-02-06 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry, 2024
6CBI	PCNA in complex with inhibitor 分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION 著者 Bruning, J.B, Wegener, K.L. 登録日 2018-02-03 公開日 2018-07-04 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry, 24, 2018
4MAZ	The Structure of MalL mutant enzyme V200S from Bacillus subtilus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. 登録日 2013-08-18 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
6OHE	Alpha-L-fucosidase AlfC D200A in complex with Fuca(1,6)GlcNAc 分子名称: AlfC, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Klontz, E.H, Sundberg, E.J. 登録日 2019-04-05 公開日 2020-04-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation. Nat Commun, 11, 2020
4MB1	The Structure of MalL mutant enzyme G202P from Bacillus subtilus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Oligo-1,6-glucosidase 1 著者 Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. 登録日 2013-08-19 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
6OH8	Crystal structure of (E)-biformene synthase LrdC from Streptomyces sp. strain K155 in the dimeric form 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Labdane-related diterpene synthase 著者 Centeno-Leija, S, Serrano-Posada, H. 登録日 2019-04-04 公開日 2019-04-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 The structure of (E)-biformene synthase provides insights into the biosynthesis of bacterial bicyclic labdane-related diterpenoids. J.Struct.Biol., 207, 2019
6R2G	Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34 分子名称: Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 著者 Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B. 登録日 2019-03-17 公開日 2019-07-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins. J.Mol.Biol., 431, 2019
6OQ1	Crystal Structure of Branched K11/K48-Linked Tri-Ubiquitin 分子名称: Ubiquitin 著者 Boughton, A.J, Fushman, D. 登録日 2019-04-25 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Branching via K11 and K48 Bestows Ubiquitin Chains with a Unique Interdomain Interface and Enhanced Affinity for Proteasomal Subunit Rpn1. Structure, 28, 2020
6R6U	Crystal structure of human cis-aconitate decarboxylase 分子名称: (R,R)-2,3-BUTANEDIOL, Cis-aconitate decarboxylase, SODIUM ION 著者 Lukat, P, Chen, F, Saile, K, Buessow, K, Pessler, F, Blankenfeldt, W. 登録日 2019-03-28 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis. Proc.Natl.Acad.Sci.USA, 116, 2019
6R2Q	Structure of the Mtr complex 分子名称: CALCIUM ION, Cystathionine beta-synthase, Decaheme c-type cytochrome, ... 著者 Clarke, T.A, Edwards, M.J. 登録日 2019-03-18 公開日 2020-04-22 最終更新日 2020-05-13 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 The Crystal Structure of a Biological Insulated Transmembrane Molecular Wire. Cell, 181, 2020
6RAA	CLK1 Kinase domain with bound imidazopyridin inhibitor TP003 分子名称: 1,2-ETHANEDIOL, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, Dual specificity protein kinase CLK1 著者 Schroeder, M, Arrowsmith, C, Knapp, S, Bountra, C, Edwards, A, Structural Genomics Consortium (SGC) 登録日 2019-04-05 公開日 2019-04-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 CLK1 Kinase domain with bound imidazopyridin inhibitor TP003 To Be Published
6RBI	Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol 分子名称: 1,2-ETHANEDIOL, 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol, Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ... 著者 Johansson, C, Newman, J.A, Kawamura, A, Schofield, C.J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2019-04-10 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol To Be Published
6RB1	Human protein kinase CK2 alpha in complex with 2-cyano-2-propenamide compound 1 分子名称: (~{E})-2-cyano-3-(3-methoxy-4-oxidanyl-phenyl)-~{N}-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... 著者 Battistutta, R, Lolli, G. 登録日 2019-04-08 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur.J.Med.Chem., 195, 2020
4OE9	The crystal structure of the n-terminal domain of COMMD9 分子名称: CITRIC ACID, COMM domain-containing protein 9, POTASSIUM ION 著者 Hospenthal, M, Celligoi, D, Lott, J.S. 登録日 2014-01-12 公開日 2015-03-04 最終更新日 2018-08-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural insights into the architecture and membrane interactions of the conserved COMMD proteins. Elife, 7, 2018
4OCT	Crystal structure of human ALKBH5 crystallized in the presence of Mn^{2+} and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA demethylase ALKBH5, ... 著者 Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-01-09 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation. J.Biol.Chem., 289, 2014
4OHQ	Crystal structure of chloroplast triose phosphate isomerase from Arabidopsis thaliana 分子名称: Triosephosphate isomerase, chloroplastic 著者 Lara-Gonzalez, S, Lopez-Castillo, M, Brieba, L.G. 登録日 2014-01-17 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Basis for Redox Regulation of Cytoplasmic and Chloroplastic Triosephosphate Isomerases from Arabidopsis thaliana. Front Plant Sci, 7, 2016
6RCB	Human protein kinase CK2 alpha in complex with 2-cyano-2-propenamide compound 14 分子名称: (~{E})-2-cyano-~{N}-(2-hydroxyphenyl)-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enamide, Casein kinase II subunit alpha, SULFATE ION 著者 Dalle Vedove, A, Lolli, G. 登録日 2019-04-11 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur.J.Med.Chem., 195, 2020
4M9F	Dengue virus NS2B-NS3 protease A125C variant at pH 8.5 分子名称: NS2B-NS3 protease 著者 Yildiz, M, Ghosh, S, Bell, J.A, Sherman, W, Hardy, J.A. 登録日 2013-08-14 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8, 2013
6DCD	Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form 分子名称: Cytochrome P450 150A6 Cyp150A6, PROTOPORPHYRIN IX CONTAINING FE 著者 Child, S.A, Bruning, J.B, Bell, S.G. 登録日 2018-05-05 公開日 2019-03-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum. Biochim Biophys Acta Gen Subj, 1863, 2019
6DXA	Crystal structure of chalcone synthase from Pinus sylvestris 分子名称: Chalcone synthase 著者 Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K. 登録日 2018-06-28 公開日 2018-10-17 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J. Biol. Chem., 293, 2018
4M9I	A125C NS2B-NS3 protease from dengue virus at pH 5.5 分子名称: NS2B-NS3 protease 著者 Yildiz, M, Hardy, J.A. 登録日 2013-08-14 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8, 2013

<70717273747576777879808182838485>