6RBI
Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol
Summary for 6RBI
Entry DOI | 10.2210/pdb6rbi/pdb |
Descriptor | Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ... (8 entities in total) |
Functional Keywords | epigenetics, kdm, lysine demethylase, chromatin, 2-oxoglutarate-dependent oxygenase, tetrazole, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 56245.75 |
Authors | Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. (deposition date: 2019-04-10, release date: 2020-05-13, Last modification date: 2024-01-24) |
Primary citation | Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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