4M9F
Dengue virus NS2B-NS3 protease A125C variant at pH 8.5
Summary for 4M9F
Entry DOI | 10.2210/pdb4m9f/pdb |
Related | 2fom 3U1I 3U1J 4M9I 4M9K 4M9M 4M9T |
Descriptor | NS2B-NS3 protease (2 entities in total) |
Functional Keywords | serine protease, allosteric inhibition, dengue virus protease, trypsin-like protease, conformational flexibility, viral protein |
Biological source | Dengue virus 2 More |
Cellular location | Virion membrane ; Multi-pass membrane protein : Q91H74 |
Total number of polymer chains | 1 |
Total formula weight | 26360.48 |
Authors | Yildiz, M.,Ghosh, S.,Bell, J.A.,Sherman, W.,Hardy, J.A. (deposition date: 2013-08-14, release date: 2013-11-27, Last modification date: 2023-09-20) |
Primary citation | Yildiz, M.,Ghosh, S.,Bell, J.A.,Sherman, W.,Hardy, J.A. Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8:2744-2752, 2013 Cited by PubMed: 24164286DOI: 10.1021/cb400612h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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