6NYI
 
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8K7C
 | | Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ... | | 著者 | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | | 登録日 | 2023-07-26 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
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5MSJ
 | | Mouse PA28alpha | | 分子名称: | Proteasome activator complex subunit 1 | | 著者 | Huber, E.M, Groll, M. | | 登録日 | 2017-01-05 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The Mammalian Proteasome Activator PA28 Forms an Asymmetric alpha 4 beta 3 Complex.
Structure, 25, 2017
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4TQI
 | | Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode | | 分子名称: | (2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid, GLYCEROL, Transthyretin | | 著者 | Stura, E.A, Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E. | | 登録日 | 2014-06-11 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
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8K7B
 | | post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound) | | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ... | | 著者 | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | | 登録日 | 2023-07-26 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
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5N0M
 | | hPAD4 crystal complex with BB-F-amidine | | 分子名称: | CALCIUM ION, Protein-arginine deiminase type-4, SULFATE ION, ... | | 著者 | Beaumont, E, Kerry, P, Thompson, P, Muth, A, Subramanian, V, Nagar, M, Srinath, H, Clancy, K, Parelkar, S. | | 登録日 | 2017-02-03 | | 公開日 | 2017-05-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
J. Med. Chem., 60, 2017
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1CM2
 | | STRUCTURE OF HIS15ASP HPR AFTER HYDROLYSIS OF RINGED SPECIES. | | 分子名称: | HISTIDINE-CONTAINING PROTEIN | | 著者 | Napper, S, Delbaere, L.T.J, Waygood, E.B. | | 登録日 | 1999-05-13 | | 公開日 | 2000-05-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The aspartyl replacement of the active site histidine in histidine-containing protein, HPr, of the Escherichia coli Phosphoenolpyruvate:Sugar phosphotransferase system can accept and donate a phosphoryl group. Spontaneous dephosphorylation of acyl-phosphate autocatalyzes an internal cyclization
J.Biol.Chem., 274, 1999
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5MYY
 | | Hen Egg-White Lysozyme (HEWL) cocrystallized in the presence of Cadmium sulphate | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Panneerselvam, S, Burkhardt, A, Meents, A. | | 登録日 | 2017-01-30 | | 公開日 | 2017-07-12 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Rapid cadmium SAD phasing at the standard wavelength (1 angstrom ).
Acta Crystallogr D Struct Biol, 73, 2017
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4ACZ
 | | Structure of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron | | 分子名称: | ENDO-ALPHA-MANNOSIDASE, GLYCEROL | | 著者 | Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J. | | 登録日 | 2011-12-21 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3P4B
 | | Alternatingly modified 2'Fluoro RNA octamer f/rA2U2-P3 | | 分子名称: | 5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3', BARIUM ION | | 著者 | Pallan, P.S, Greene, E.M, Jicman, P.A, Pandey, R.K, Manoharan, M, Rozners, E, Egli, M. | | 登録日 | 2010-10-06 | | 公開日 | 2011-01-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.
Nucleic Acids Res., 39, 2011
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5DO8
 | | 1.8 Angstrom crystal structure of Listeria monocytogenes Lmo0184 alpha-1,6-glucosidase | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Lmo0184 protein, ... | | 著者 | Light, S.H, Halavaty, A.S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-09-10 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure to function of an alpha-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.
Nat Microbiol, 2, 2016
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3OOW
 | | Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, F.W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-08-31 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.
To be Published
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5USH
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4DGG
 | | c-SRC kinase domain in complex with RM-1-176 | | 分子名称: | 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Merritt, E.A, Larson, E.T. | | 登録日 | 2012-01-25 | | 公開日 | 2012-10-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Active site profiling reveals coupling between domains in SRC-family kinases.
Nat.Chem.Biol., 9, 2013
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2SOD
 | | DETERMINATION AND ANALYSIS OF THE 2 ANGSTROM STRUCTURE OF COPPER, ZINC SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Tainer, J.A, Getzoff, E.D, Richardson, J.S, Richardson, D.C. | | 登録日 | 1980-03-25 | | 公開日 | 1980-05-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase.
J.Mol.Biol., 160, 1982
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7FIJ
 | | luteinizing hormone/choriogonadotropin receptor | | 分子名称: | Lutropin-choriogonadotropic hormone receptor | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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4RED
 | | Crystal structure of human AMPK alpha1 KD-AID with K43A mutation | | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | | 著者 | Zhou, X.E, Ke, J, Li, X, Wang, L, Gu, X, de Waal, P.W, Tan, M.H.E, Wang, D, Wu, D, Xu, H.E, Melcher, K. | | 登録日 | 2014-09-22 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
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5DA5
 | | Crystal structure of Rhodospirillum rubrum Rru_A0973 | | 分子名称: | CALCIUM ION, FE (III) ION, GLYCOLIC ACID, ... | | 著者 | He, D, Vanden Hehier, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. | | 登録日 | 2015-08-19 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.064 Å) | | 主引用文献 | Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments.
Elife, 5, 2016
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1Q3G
 | | MurA (Asp305Ala) liganded with tetrahedral reaction intermediate | | 分子名称: | 1,2-ETHANEDIOL, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, UDP-N-acetylglucosamine 1-carboxyvinyltransferase | | 著者 | Eschenburg, S, Kabsch, W, Healy, M.L, Schonbrunn, E. | | 登録日 | 2003-07-29 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States.
J.Biol.Chem., 278, 2003
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1JEB
 | | Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human Zeta2 / Mouse Beta2) | | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN BETA-SINGLE CHAIN, HEMOGLOBIN ZETA CHAIN, ... | | 著者 | Kidd, R.D, Russell, J.E, Watmough, N.J, Baker, E.N, Brittain, T. | | 登録日 | 2001-06-17 | | 公開日 | 2002-01-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The role of beta chains in the control of the hemoglobin oxygen binding function: chimeric human/mouse proteins, structure, and function.
Biochemistry, 40, 2001
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4KBS
 | | Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 phosphatidic acid (12:0 PA) | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Glycolipid transfer protein domain-containing protein 1 | | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | | 登録日 | 2013-04-23 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
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2NWG
 | | Structure of CXCL12:heparin disaccharide complex | | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1 | | 著者 | Murphy, J.W, Cho, Y, Lolis, E. | | 登録日 | 2006-11-14 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin
J.Biol.Chem., 282, 2007
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1L1O
 | | Structure of the human Replication Protein A (RPA) trimerization core | | 分子名称: | Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ... | | 著者 | Bochkareva, E.V, Korolev, S, Lees-Miller, S.P, Bochkarev, A. | | 登録日 | 2002-02-19 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.
EMBO J., 21, 2002
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4NKY
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3E13
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