PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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8PLB	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 12. 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-ethyl-4-[(methylsulfonyl)amino]benzamide, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
8PLN	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 24. 分子名称: 6,7,8,9-tetrahydro-5~{H}-carbazole-1-carbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
8PLO	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 25. 分子名称: 2-(4-methylphenyl)-N-{[(2S)-oxolan-2-yl]methyl}acetamide, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
7U5O	CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B 分子名称: Bone morphogenetic protein receptor type-2, Inhibin beta B chain 著者 Chu, K.Y, Malik, A, Thamilselvan, V, Martinez-Hackert, E. 登録日 2022-03-02 公開日 2022-06-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298, 2022
8PLW	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 33. 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase, methyl 4-(4-fluorophenyl)piperazine-1-carboxylate 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
7R84	Structure of mouse BAI1 (ADGRB1) TSR3 domain in P21 space group 分子名称: Vasculostatin-120, alpha-D-mannopyranose, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose 著者 Miao, Y, Jude, K.M, Garcia, K.C. 登録日 2021-06-26 公開日 2021-11-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.336 Å) 主引用文献 RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development. Cell, 184, 2021
8PLC	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 13. 分子名称: (1~{R})-1-(4-ethoxyphenyl)ethanamine, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
8PLR	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 28. 分子名称: (2R)-1-{[(5-methylthiophen-2-yl)methyl]amino}propan-2-ol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
7OZR	Subtomogram average of authentic mumps virus nucleocapsid from HeLa cell lysate of long helical pitch 分子名称: Nucleocapsid, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3') 著者 Mahamid, J, Zhang, X. 登録日 2021-06-28 公開日 2023-03-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Molecular mechanisms of stress-induced reactivation in mumps virus condensates. Cell, 186, 2023
8PLP	Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 26. 分子名称: (3R)-1-methylpiperidin-3-yl furan-2-carboxylate, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase 著者 Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. 登録日 2023-06-27 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14, 2024
7U5P	CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2A, Inhibin beta A chain 著者 Chu, K.Y, Malik, A, Thamilselvan, V, Martinez-Hackert, E. 登録日 2022-03-02 公開日 2022-06-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298, 2022
4RP5	Crystal Structure of the L27 domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster (space group P21) 分子名称: CHLORIDE ION, Disks large 1 tumor suppressor protein 著者 Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-10-29 公開日 2014-11-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module. Biochemistry, 57, 2018
8PD9	cAMP-bound SpSLC9C1 in lipid nanodiscs, protomer state 1 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger 著者 Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. 登録日 2023-06-12 公開日 2023-11-08 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
8PDV	cGMP-bound SpSLC9C1 in lipid nanodiscs, protomer 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger 著者 Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. 登録日 2023-06-12 公開日 2023-11-08 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
7PZR	Cryo-EM structure of POLRMT in free form. 分子名称: DNA-directed RNA polymerase, mitochondrial 著者 Das, H, Hallberg, B.M. 登録日 2021-10-13 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
8PDU	cGMP-bound SpSLC9C1 in lipid nanodiscs, dimer 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger 著者 Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. 登録日 2023-06-12 公開日 2023-11-08 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
4WK0	Metal Ion and Ligand Binding of Integrin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-GLY-ASP, ... 著者 Xia, W, Springer, T.A. 登録日 2014-10-01 公開日 2014-12-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Metal ion and ligand binding of integrin alpha 5 beta 1. Proc.Natl.Acad.Sci.USA, 111, 2014
7TJL	Crystal structure of de novo designed protein, SEWN0.1 分子名称: De novo designed protein, SEWN0.1 著者 Cummins, M.C, Jacobs, T.M, Kuhlman, B. 登録日 2022-01-16 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 AlphaFold accurately predicts distinct conformations based on the oligomeric state of a de novo designed protein Protein Sci., 31, 2022
7RE5	Crystal Structure of The Tetramerization Domain (29-147) From Human Voltage-gated Potassium Channel Kv2.1 in P 41 21 2 Space Group 分子名称: Potassium voltage-gated channel subfamily B member 1, ZINC ION 著者 Xu, Z, Schnicker, N, Baker, S. 登録日 2021-07-12 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pentameric assembly of the Kv2.1 tetramerization domain. Acta Crystallogr D Struct Biol, 78, 2022
6QSK	Crystal structure of a nucleotide sugar transporter with bound nucleotide monophosphate. 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GDP-mannose transporter 1, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Newstead, S, Parker, J.L. 登録日 2019-02-21 公開日 2019-10-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.394 Å) 主引用文献 Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer. Nat Commun, 10, 2019
4WHV	E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B 分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... 著者 Hodge, C.D, Edwards, R.A, Glover, J.N.M. 登録日 2014-09-23 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (8.3 Å) 主引用文献 RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
8PBD	RAD51 filament on dsDNA bound by the BRCA2 c-terminus 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ... 著者 Appleby, R, Pellegrini, L. 登録日 2023-06-09 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2. Nat Commun, 14, 2023
8EPL	Human R-type voltage-gated calcium channel Cav2.3 at 3.1 Angstrom resolution 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gao, S, Yao, X, Yan, N. 登録日 2022-10-06 公開日 2022-12-14 最終更新日 2023-07-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments. Nat Commun, 13, 2022
4WJK	Metal Ion and Ligand Binding of Integrin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Xia, W, Springer, T.A. 登録日 2014-09-30 公開日 2014-12-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal ion and ligand binding of integrin alpha 5 beta 1. Proc.Natl.Acad.Sci.USA, 111, 2014
8PBC	RAD51 filament on ssDNA bound by the BRCA2 c-terminus 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ... 著者 Appleby, R, Pellegrini, L. 登録日 2023-06-09 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.61 Å) 主引用文献 Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2. Nat Commun, 14, 2023

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