7U5O

CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B

Summary for 7U5O

Entry DOI	10.2210/pdb7u5o/pdb
Descriptor	Inhibin beta B chain, Bone morphogenetic protein receptor type-2 (2 entities in total)
Functional Keywords	cell signaling, receptor-ligand complex, growth factor, receptor interaction, activin b, bmprii, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	75759.95
Authors	Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. (deposition date: 2022-03-02, release date: 2022-06-22, Last modification date: 2023-10-18)
Primary citation	Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298:102076-102076, 2022 Cited by PubMed: 35643319 DOI: 10.1016/j.jbc.2022.102076 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.45 Å)

Structure validation