7U5O

CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008083	molecular_function	growth factor activity
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity
C	0005576	cellular_component	extracellular region
C	0008083	molecular_function	growth factor activity
E	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
E	0005524	molecular_function	ATP binding
E	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
E	0016020	cellular_component	membrane
F	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
F	0005524	molecular_function	ATP binding
F	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
F	0016020	cellular_component	membrane
G	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
G	0005524	molecular_function	ATP binding
G	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
G	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IiaPtgYygnyCeGsC

Chain	Residue	Details
A	ILE321-CYS336

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
E	ASN55
E	ASN110
E	ASN126
F	ASN55
F	ASN110
F	ASN126
G	ASN55
G	ASN110
G	ASN126

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