PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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4OI8	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. 分子名称: 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', Advanced glycosylation end product-specific receptor 著者 Jin, T, Jiang, J, Xiao, T. 登録日 2014-01-19 公開日 2014-04-30 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
3UMI	X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with zinc 分子名称: ACETATE ION, Amyloid beta A4 protein, CADMIUM ION, ... 著者 Dahms, S.O, Konnig, I, Roeser, D, Guhrs, K.H, Than, M.E. 登録日 2011-11-13 公開日 2012-01-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain. J.Mol.Biol., 416, 2012
4OGQ	Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex 分子名称: (1R)-1-{[(2S)-3-hydroxy-2-{[(1R)-1-hydroxypentyl]oxy}propyl]oxy}hexan-1-ol, (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (1S,8E)-1-{[(2S)-1-hydroxy-3-{[(1S)-1-hydroxypentadecyl]oxy}propan-2-yl]oxy}heptadec-8-en-1-ol, ... 著者 Hasan, S.S, Cramer, W.A. 登録日 2014-01-16 公開日 2014-05-14 最終更新日 2021-03-10 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex. Structure, 22, 2014
4OHI	LEOPARD Syndrome-Associated SHP2/Q510E mutant 分子名称: Tyrosine-protein phosphatase non-receptor type 11 著者 Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. 登録日 2014-01-17 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry, 53, 2014
3V6F	Crystal Structure of an anti-HBV e-antigen monoclonal Fab fragment (e6), unbound 分子名称: Fab e6 Heavy Chain, Fab e6 Light Chain 著者 Dimattia, M.A, Watts, N.R, Stahl, S.J, Grimes, J.M, Steven, A.C, Stuart, D.I, Wingfield, P.T. 登録日 2011-12-19 公開日 2013-02-06 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein. Structure, 21, 2013
3UN5	Bacillus cereus phosphopentomutase T85E variant 分子名称: GLYCEROL, MANGANESE (II) ION, Phosphopentomutase 著者 Iverson, T.M, Birmingham, W.R, Panosian, T.D, Nannemann, D.P, Bachmann, B.O. 登録日 2011-11-15 公開日 2012-02-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular Differences between a Mutase and a Phosphatase: Investigations of the Activation Step in Bacillus cereus Phosphopentomutase. Biochemistry, 51, 2012
4OK0	Crystal structure of putative nucleotidyltransferase from H. pylori 分子名称: Putative 著者 Yoon, J.Y, Lee, S.J, Lee, B, Yang, J.K, Suh, S.W. 登録日 2014-01-21 公開日 2014-04-09 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Crystal structure of JHP933 from Helicobacter pylori J99 shows two-domain architecture with a DUF1814 family nucleotidyltransferase domain and a helical bundle domain. Proteins, 82, 2014
3UJC	Phosphoethanolamine methyltransferase mutant (H132A) from Plasmodium falciparum in complex with phosphocholine 分子名称: PHOSPHOCHOLINE, Phosphoethanolamine N-methyltransferase 著者 Lee, S.G, Kim, Y, Alpert, T.D, Nagata, A, Jez, J.M. 登録日 2011-11-07 公開日 2011-11-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target. J.Biol.Chem., 287, 2012
4OHZ	bound to ssRNA tetranucleotide GAAA, ADP, and Mg2+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... 著者 Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. 登録日 2014-01-18 公開日 2014-05-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
3UO7	Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Zhang, L, He, C. 登録日 2011-11-16 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8, 2012
4OKL	Crystal Structure of d(CCCCGGTACCGGGG)2 at 1.65 Angstrom 分子名称: 14 mer A-DNA 著者 Anna, V, Monica, P, Mandal, P.K, Gautham, N. 登録日 2014-01-22 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of d(CCCCGGTACCGGGG)2 at 1.65 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 70, 2014
2RD0	Structure of a human p110alpha/p85alpha complex 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Huang, C, Gabelli, S.B, Amzel, L.M. 登録日 2007-09-20 公開日 2007-12-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science, 318, 2007
4OIB	Crystal Structure of ICAM-5 D1-D4 ectodomain fragment, Space Group R3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule 5, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Recacha, R, Jimenez, D, Tian, L, Barredo, R, Ghamberg, C, Casasnovas, J.M. 登録日 2014-01-19 公開日 2014-07-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.503 Å) 主引用文献 Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions. Acta Crystallogr.,Sect.D, 70, 2014
4H79	Crystal structure of CasB from Thermobifida fusca 分子名称: 1,2-ETHANEDIOL, CRISPR-associated protein, Cse2 family 著者 Ke, A, Nam, K.H. 登録日 2012-09-20 公開日 2012-10-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures. Febs Lett., 586, 2012
3UON	Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist 分子名称: (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, CHLORIDE ION, Human M2 muscarinic acetylcholine, ... 著者 Haga, K, Kruse, A.C, Asada, H, Yurugi-Kobayashi, T, Shiroishi, M, Zhang, C, Weis, W.I, Okada, T, Kobilka, B.K, Haga, T, Kobayashi, T. 登録日 2011-11-16 公開日 2012-02-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature, 482, 2012
4OKQ	Crystal structure of the single-stranded RNA binding protein HutP from Geobacillus thermodenitrificans 分子名称: HISTIDINE, Hut operon positive regulatory protein, MAGNESIUM ION 著者 Thiruselvam, V, Ponnuswamy, M.N, Kumarevel, T.S. 登録日 2014-01-22 公開日 2014-03-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the single-stranded RNA binding protein HutP from Geobacillus thermodenitrificans Biochem.Biophys.Res.Commun., 446, 2014
3UJP	Structure of MntC protein at 2.7A 分子名称: CACODYLATE ION, MANGANESE (II) ION, Mn transporter subunit, ... 著者 Kanteev, M, Adir, N. 登録日 2011-11-08 公開日 2012-11-14 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Arginine 116 stabilizes the entrance to the metal ion-binding site of the MntC protein. Acta Crystallogr.,Sect.F, 69, 2013
4OKZ	Selinadiene Synthase in complex with dihydrofarnesyl pyrophosphate 分子名称: (3S,6E)-3,7,11-trimethyldodeca-6,10-dien-1-yl trihydrogen diphosphate, MAGNESIUM ION, Terpene synthase metal-binding domain-containing protein 著者 Baer, P, Rabe, P, Fischer, K, Citron, C.A, Klapschinski, T, Groll, M, Dickschat, J.S. 登録日 2014-01-23 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Induced-fit mechanism in class i terpene cyclases. Angew.Chem.Int.Ed.Engl., 53, 2014
4OJV	Crystal structure of unliganded yeast PDE1 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3',5'-cyclic-nucleotide phosphodiesterase 1, SULFATE ION, ... 著者 Tian, Y, Cui, W, Huang, M, Robinson, H, Wan, Y, Wang, Y, Ke, H. 登録日 2014-01-21 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate. Biochemistry, 53, 2014
3UP8	Crystal structure of a putative 2,5-diketo-D-gluconic acid reductase B 分子名称: ACETATE ION, Putative 2,5-diketo-D-gluconic acid reductase B 著者 Eswaramoorthy, S, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2011-11-17 公開日 2011-12-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structure of a putative 2,5-diketo-D-gluconic acid reductase B To be Published
3UK6	Crystal Structure of the Tip48 (Tip49b) hexamer 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 2 著者 Petukhov, M, Dagkessamanskaja, A, Bommer, M, Barrett, T, Tsaneva, I, Yakimov, A, Queval, R, Shvetsov, A, Khodorkovskiy, M, Kas, E, Grigoriev, M. 登録日 2011-11-09 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases. Structure, 20, 2012
4OK4	Crystal Structure of Alg17c Mutant H202L 分子名称: Putative alginate lyase, ZINC ION 著者 Nair, S.K, Park, D.S. 登録日 2014-01-21 公開日 2014-01-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases. J.Biol.Chem., 289, 2014
3UPH	Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitors 分子名称: 6-(2,5-difluorobenzyl)-N-(methylsulfonyl)-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase 著者 Velazquez, F, Venkataraman, S, Lesburg, C.A, Duca, J.S, Rosenblum, S.B, Kozlowski, J.A, Njoroge, F.G. 登録日 2011-11-18 公開日 2012-01-25 最終更新日 2012-02-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis of New 4,5-Dihydrofuranoindoles and Their Evaluation as HCV NS5B Polymerase Inhibitors. Org.Lett., 14, 2012
3ULQ	Crystal Structure of the Anti-Activator RapF Complexed with the Response Regulator ComA DNA Binding Domain 分子名称: MANGANESE (II) ION, Response regulator aspartate phosphatase F, Transcriptional regulatory protein ComA 著者 Baker, M.D, Neiditch, M.B. 登録日 2011-11-11 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of response regulator inhibition by a bacterial anti-activator protein. Plos Biol., 9, 2011
3ULU	Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... 著者 Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. 登録日 2011-11-11 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012

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