8EAJ
 
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 1 | | 分子名称: | 46-mer DNA strand, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | 著者 | Meagher, M, Myasnikov, A, Enemark, E.J. | | 登録日 | 2022-08-29 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | | 主引用文献 | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAF
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 1 | | 分子名称: | 12-mer oligo dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | 著者 | Meagher, M, Myasnikov, A, Enemark, E.J. | | 登録日 | 2022-08-29 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAG
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2 | | 分子名称: | 12-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | 著者 | Meagher, M, Myasnikov, A, Enemark, E.J. | | 登録日 | 2022-08-29 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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6QGG
 | | Structure of human Bcl-2 in complex with analogue of ABT-737 | | 分子名称: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1, [(3~{R})-3-[[4-[[4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]phenyl]carbonylsulfamoyl]-2-nitro-phenyl]amino]-4-phenylsulfanyl-butyl]-(2-hydroxy-2-oxoethyl)-dimethyl-azanium | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6O9M
 | | Structure of the human apo TFIIH | | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ... | | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | | 登録日 | 2019-03-14 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
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6ODE
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8DYV
 | | Structure of human cytoplasmic dynein-1 bound to one Lis1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | 著者 | Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E. | | 登録日 | 2022-08-05 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.
Elife, 12, 2023
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6OFH
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8DYU
 | | Structure of human cytoplasmic dynein-1 bound to two Lis1 proteins | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | 著者 | Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E. | | 登録日 | 2022-08-05 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.
Elife, 12, 2023
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6OQR
 | | E. coli ATP Synthase ADP State 1a | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | 著者 | Stewart, A.G, Walshe, J.L, Sobti, M. | | 登録日 | 2019-04-29 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch.
Nat Commun, 11, 2020
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8OIC
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6OQS
 | | E. coli ATP synthase State 1b | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | 著者 | Stewart, A.G, Sobti, M, Walshe, J.L. | | 登録日 | 2019-04-29 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch.
Nat Commun, 11, 2020
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8K4W
 | | Structure of a triple-helix region of human collagen type I from Trautec | | 分子名称: | CHLORIDE ION, triple-helix region of human collagen type I | | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | 登録日 | 2023-07-20 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a triple-helix region of human collagen type I from Trautec.
To Be Published
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6ONS
 | | Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase with the D-cluster ligating cysteines mutated to alanines, coexpressed with CooC, as-isolated | | 分子名称: | Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, IRON/SULFUR CLUSTER | | 著者 | Cohen, S.E, Wittenborn, E.C, Drennan, C.L. | | 登録日 | 2019-04-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.485 Å) | | 主引用文献 | Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
J.Biol.Chem., 294, 2019
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8DY7
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8E3G
 | | BMP2/GDF5 heterodimer | | 分子名称: | Bone morphogenetic protein 2, GLYCEROL, Growth/differentiation factor 5 | | 著者 | Gipson, G.R, Nolan, K.T, Thompson, T.B. | | 登録日 | 2022-08-17 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
Bmc Biol., 21, 2023
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8DPB
 | | MeaB in complex with the cobalamin-binding domain of its target mutase with GMPPCP bound | | 分子名称: | GLYCEROL, MAGNESIUM ION, Methylmalonyl-CoA mutase accessory protein, ... | | 著者 | Vaccaro, F.A, Born, D.A, Drennan, C.L. | | 登録日 | 2022-07-15 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structure of metallochaperone in complex with the cobalamin-binding domain of its target mutase provides insight into cofactor delivery.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DY9
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8JOH
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8DSG
 | | P411-PFA carbene transferase | | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450-BM3 variant P411-PFA, ... | | 著者 | Maggiolo, A.O, Porter, N.J, Zhang, J, Arnold, F.H. | | 登録日 | 2022-07-22 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Chemodivergent C(sp 3 )-H and C(sp 2 )-H Cyanomethylation Using Engineered Carbene Transferases.
Nat Catal, 6, 2023
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8E74
 | | Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2022-08-23 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
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8E82
 | | Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
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8DXP
 | | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3 | | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | | 登録日 | 2022-08-02 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
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6QKL
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8DXQ
 | | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4 | | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | | 登録日 | 2022-08-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
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