8DSG

P411-PFA carbene transferase

Summary for 8DSG

Entry DOI	10.2210/pdb8dsg/pdb
Descriptor	Cytochrome P450-BM3 variant P411-PFA, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	cytochrome p450, carbene transferase, cyanomethylase, fluoroalkylation, oxidoreductase
Biological source	Priestia megaterium
Total number of polymer chains	4
Total formula weight	219841.37
Authors	Maggiolo, A.O.,Porter, N.J.,Zhang, J.,Arnold, F.H. (deposition date: 2022-07-22, release date: 2023-03-08, Last modification date: 2024-05-01)
Primary citation	Zhang, J.,Maggiolo, A.O.,Alfonzo, E.,Mao, R.,Porter, N.J.,Abney, N.,Arnold, F.H. Chemodivergent C(sp 3 )-H and C(sp 2 )-H Cyanomethylation Using Engineered Carbene Transferases. Nat Catal, 6:152-160, 2023 Cited by PubMed: 36875868 DOI: 10.1038/s41929-022-00908-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation