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1Q2B
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CELLOBIOHYDROLASE CEL7A WITH DISULPHIDE BRIDGE ADDED ACROSS EXO-LOOP BY MUTATIONS D241C AND D249C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, EXOCELLOBIOHYDROLASE I
著者Stahlberg, J, Harris, M, Jones, T.A.
登録日2003-07-24
公開日2003-11-25
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D.
J.Mol.Biol., 333, 2003
1Q2C
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Crystal Structure of Tetrahymena GCN5 With Bound Coenzyme A and a 19-residue Histone H4 Peptide
分子名称: COENZYME A, Histone H4 peptide, histone acetyltransferase GCN5
著者Poux, A.N, Marmorstein, R.
登録日2003-07-24
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase
Mol.Cell, 12, 2003
1Q2D
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Crystal Structure of Tetrahymena GCN5 With Bound Coenzyme A and a 19-residue p53 peptide
分子名称: 19-mer peptide fragment from p53 Tumor Suppressor, COENZYME A, histone acetyltransferase GCN5
著者Poux, A.N, Marmorstein, R.
登録日2003-07-24
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular basis for GCN5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates
Biochemistry, 42, 2003
1Q2E
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CELLOBIOHYDROLASE CEL7A WITH LOOP DELETION 245-252 AND BOUND NON-HYDROLYSABLE CELLOTETRAOSE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EXOCELLOBIOHYDROLASE I, ...
著者Stahlberg, J, Harris, M, Jones, T.A.
登録日2003-07-24
公開日2003-11-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D
J.Mol.Biol., 333, 2003
1Q2F
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NMR SOLUTION STRUCTURE OF A PEPTIDE FROM THE MDM-2 BINDING DOMAIN OF THE P53 PROTEIN THAT IS SELECTIVELY CYTOTOXIC TO CANCER CELLS
分子名称: PNC27
著者Rosal, R, Pincus, M.R, Brandt-Rauf, P.W, Fine, R.L, Wang, H.
登録日2003-07-24
公開日2004-03-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells
Biochemistry, 43, 2004
1Q2H
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Phenylalanine Zipper Mediates APS Dimerization
分子名称: adaptor protein with pleckstrin homology and src homology 2 domains
著者Dhe-Paganon, S, Werner, E.D, Nishi, M, Chi, Y.-I, Shoelson, S.E.
登録日2003-07-24
公開日2004-08-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A phenylalanine zipper mediates APS dimerization.
Nat.Struct.Mol.Biol., 11, 2004
1Q2I
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NMR SOLUTION STRUCTURE OF A PEPTIDE FROM THE MDM-2 BINDING DOMAIN OF THE P53 PROTEIN THAT IS SELECTIVELY CYTOTOXIC TO CANCER CELLS
分子名称: PNC27
著者Rosal, R, Pincus, M.R, Brandt-Rauf, P.W, Fine, R.L, Wang, H.
登録日2003-07-24
公開日2004-03-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells
Biochemistry, 43, 2004
1Q2J
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Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA
分子名称: Mu-conotoxin SmIIIA
著者Keizer, D.W, West, P.J, Lee, E.F, Olivera, B.M, Bulaj, G, Yoshikami, D, Norton, R.S.
登録日2003-07-24
公開日2004-02-24
最終更新日2020-06-24
実験手法SOLUTION NMR
主引用文献Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.
J.Biol.Chem., 278, 2003
1Q2K
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Solution structure of BmBKTx1 a new potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
分子名称: Neurotoxin BmK37
著者Cai, Z, Xu, C, Xu, Y, Lu, W, Chi, C.W, Shi, Y, Wu, J.
登録日2003-07-25
公開日2003-09-09
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution Structure of BmBKTx1, a New BK(Ca)(1) Channel Blocker from the Chinese Scorpion Buthus martensi Karsch(,).
Biochemistry, 43, 2004
1Q2L
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Crystal Structure of pitrilysin
分子名称: PLATINUM (II) ION, Protease III, ZINC ION
著者Maskos, K, Jozic, D, Fernandez-Catalan, C.
登録日2003-07-25
公開日2005-05-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of pitrilysin, the prototype of insulin-degrading enzymes
To be Published
1Q2N
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REFINED Solution NMR structure of the Z domain of STAPHYLOCOCCAL PROTEIN A
分子名称: IMMUNOGLOBULIN G BINDING PROTEIN A
著者Zheng, D, Tashiro, M, Aramini, J.M, Montelione, G.T.
登録日2003-07-25
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Validation of helical tilt angles in the solution NMR structure of the Z domain of Staphylococcal protein A by combined analysis of residual dipolar coupling and NOE data.
Protein Sci., 13, 2004
1Q2O
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Bovine endothelial nitric oxide synthase N368D mutant heme domain dimer with L-N(omega)-nitroarginine-2,4-L-diaminobutyramide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-07-25
公開日2004-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1Q2P
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SHV-1 class A beta-lactamase complexed with penem WAY185229
分子名称: (6,7-DIHYDRO-5H-CYCLOPENTA[D]IMIDAZO[2,1-B]THIAZOL-2-YL]-4,7-DIHYDRO[1,4]THIAZEPINE-3,6-DICARBOXYLIC ACID, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, beta-lactamase SHV-1
著者Nukaga, M, Venkatesan, A.M, Mansour, T.S, Hujer, A, Bonomo, R.A, Knox, J.R.
登録日2003-07-25
公開日2004-09-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates
J.Med.Chem., 47, 2004
1Q2Q
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Enterobacter cloacae GC1 class C beta-lactamase complexed with penem WAY185229
分子名称: (6,7-DIHYDRO-5H-CYCLOPENTA[D]IMIDAZO[2,1-B]THIAZOL-2-YL]-4,7-DIHYDRO[1,4]THIAZEPINE-3,6-DICARBOXYLIC ACID, GLYCEROL, class C beta-lactamase
著者Nukaga, M, Venkatesan, A.M, Mansour, T.S, Hujer, A, Bonomo, R.A, Knox, J.R.
登録日2003-07-25
公開日2004-09-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates
J.Med.Chem., 47, 2004
1Q2R
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Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
分子名称: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), ...
著者Xie, W, Liu, X, Huang, R.H.
登録日2003-07-25
公開日2003-09-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
1Q2S
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Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
分子名称: 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, ...
著者Xie, W, Liu, X, Huang, R.H.
登録日2003-07-25
公開日2003-09-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
1Q2T
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Solution structure of d(5mCCTCTCC)4
分子名称: 5'-D(*(MCY)P*CP*TP*CP*TP*CP*C)-3'
著者Leroy, J.-L.
登録日2003-07-26
公開日2003-09-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献T.T pair intercalation and duplex inter-conversion within i-motif tetramers
J.Mol.Biol., 333, 2003
1Q2U
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Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
分子名称: RNA-binding protein regulatory subunit
著者Huai, Q, Sun, Y, Wang, H, Chin, L.S, Li, L, Robinson, H, Ke, H.
登録日2003-07-26
公開日2003-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
Febs Lett., 549, 2003
1Q2V
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Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form)
分子名称: SULFATE ION, Thermosome alpha subunit
著者Shomura, Y, Yoshida, T, Iizuka, R, Yohda, M, Maruyama, T, Miki, K.
登録日2003-07-26
公開日2004-01-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms.
J.Mol.Biol., 335, 2004
1Q2W
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X-Ray Crystal Structure of the SARS Coronavirus Main Protease
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3C-like protease
著者Bonanno, J.B, Fowler, R, Gupta, S, Hendle, J, Lorimer, D, Romero, R, Sauder, J.M, Wei, C.L, Liu, E.T, Burley, S.K, Harris, T.
登録日2003-07-26
公開日2003-07-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Company Says It Mapped Part of SARS Virus
New York Times, 30 July, 2003
1Q2X
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Crystal Structure of the E243D Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae bound with substrate aspartate semialdehyde
分子名称: Aspartate-semialdehyde dehydrogenase
著者Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
登録日2003-07-26
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1Q2Y
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Crystal structure of the protein YJCF from Bacillus subtilis: a member of the GCN5-related N-acetyltransferase superfamily fold
分子名称: similar to hypothetical proteins
著者Fedorov, A.A, Ramagopal, U.A, Fedorov, E.V, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-07-27
公開日2003-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the protein YJCF from Bacillus subtilis: a member of the GCN5-related N-acetyltransferase superfamily
To be Published
1Q2Z
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The 3D solution structure of the C-terminal region of Ku86
分子名称: ATP-dependent DNA helicase II, 80 kDa subunit
著者Harris, R, Esposito, D, Sankar, A, Maman, J.D, Hinks, J.A, Pearl, L.H, Driscoll, P.C.
登録日2003-07-28
公開日2004-01-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The 3D Solution Structure of the C-terminal Region of Ku86 (Ku86CTR)
J.Mol.Biol., 335, 2004
1Q31
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Crystal Structure of the Tobacco Etch Virus Protease C151A mutant
分子名称: BETA-MERCAPTOETHANOL, Nuclear inclusion protein A
著者Nunn, C.M, Djordjevic, S, George, R.R, Urquhart, G.T, Chao, L.H, Tsuchiya, Y.
登録日2003-07-28
公開日2004-11-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site.
J.Mol.Biol., 350, 2005
1Q32
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Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase
分子名称: tyrosyl-DNA phosphodiesterase
著者He, X, Babaoglu, K, Price, A, Nitiss, K.C, Nitiss, J.L, White, S.W.
登録日2003-07-28
公開日2004-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison
J.Mol.Biol., 372, 2007

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