1Q2W

X-Ray Crystal Structure of the SARS Coronavirus Main Protease

Summary for 1Q2W

Descriptor3C-like protease, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywordssars-cov main protease, three domain protein (two antiparallel beta barrels, one alpha helical), hydrolase
Biological sourceSevere acute respiratory syndrome-related coronavirus (SARS-CoV)
Total number of polymer chains2
Total molecular weight68093.63
Authors
Bonanno, J.B.,Fowler, R.,Gupta, S.,Hendle, J.,Lorimer, D.,Romero, R.,Sauder, J.M.,Wei, C.L.,Liu, E.T.,Burley, S.K.,Harris, T. (deposition date: 2003-07-26, release date: 2003-07-29, Last modification date: 2020-02-26)
Primary citation
Bonanno, J.B.,Fowler, R.,Gupta, S.,Hendle, J.,Lorimer, D.,Romero, R.,Sauder, J.M.,Wei, C.L.,Liu, E.T.,Burley, S.K.,Harris, T.
Company Says It Mapped Part of SARS Virus
New York Times, 30 July:C2-C2, 2003
Experimental method
X-RAY DIFFRACTION (1.86 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24170 3.7% 4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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