1Q2W

X-Ray Crystal Structure of the SARS Coronavirus Main Protease

Summary for 1Q2W

• Entry DOI: 10.2210/pdb1q2w/pdb
• Descriptor: 3C-like protease, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• Functional Keywords: sars-cov main protease, three domain protein (two antiparallel beta barrels, one alpha helical), hydrolase
• Biological source: Severe acute respiratory syndrome-related coronavirus (SARS-CoV)
• Total number of polymer chains: 2
• Total formula weight: 68093.63

Authors

Bonanno, J.B.,Fowler, R.,Gupta, S.,Hendle, J.,Lorimer, D.,Romero, R.,Sauder, J.M.,Wei, C.L.,Liu, E.T.,Burley, S.K.,Harris, T. (deposition date: 2003-07-26, release date: 2003-07-29, Last modification date: 2023-08-16)

• Primary citation: Bonanno, J.B.,Fowler, R.,Gupta, S.,Hendle, J.,Lorimer, D.,Romero, R.,Sauder, J.M.,Wei, C.L.,Liu, E.T.,Burley, S.K.,Harris, T.; Company Says It Mapped Part of SARS Virus; New York Times, 30 July:C2-C2, 2003

Experimental method

X-RAY DIFFRACTION (1.86 Å)