1Q2W
X-Ray Crystal Structure of the SARS Coronavirus Main Protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like protease | polymer | 308 | 33987.7 | 2 | UniProt (P0C6U8) Pfam (PF05409) | Severe acute respiratory syndrome-related coronavirus (SARS-CoV) | 3C-like proteinase, 3CL-PRO, 3CLp, nsp5 |
| 2 | C (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 304 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Glu 305 | - | expression tag |
| Gly 306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67975.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 118.2 | |
| All* | Total formula weight | 68093.6 |
