1Q2O

Bovine endothelial nitric oxide synthase N368D mutant heme domain dimer with L-N(omega)-nitroarginine-2,4-L-diaminobutyramide bound

Summary for 1Q2O

Entry DOI	10.2210/pdb1q2o/pdb
Related	1P6H 1P6I 1P6J 1P6K 1P6L 1P6M 1P6N
Descriptor	Nitric-oxide synthase, endothelial, CACODYLATE ION, ACETATE ION, ... (9 entities in total)
Functional Keywords	oxidoreductase, endothelial nitric oxide synthase, enos, nos iii, heme protein
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane: P29473
Total number of polymer chains	2
Total formula weight	96703.82
Authors	Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2003-07-25, release date: 2004-01-13, Last modification date: 2024-04-03)
Primary citation	Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11:54-59, 2004 Cited by PubMed: 14718923 DOI: 10.1038/nsmb704 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation