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1P6K

Rat neuronal NOS D597N mutant heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound

Summary for 1P6K
Entry DOI10.2210/pdb1p6k/pdb
Related1P6H 1P6I 1P6J 1P6L 1P6M 1P6N
DescriptorNitric-oxide synthase, brain, D-MANNITOL, ACETATE ION, ... (8 entities in total)
Functional Keywordsnitric oxide synthase, oxidoreductase, heme-enzyme
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCell membrane, sarcolemma; Peripheral membrane protein (By similarity): P29476
Total number of polymer chains2
Total formula weight100408.96
Authors
Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.-M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2003-04-29, release date: 2004-01-13, Last modification date: 2024-02-14)
Primary citationFlinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L.
Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11:54-59, 2004
Cited by
PubMed: 14718923
DOI: 10.1038/nsmb704
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.78 Å)
Structure validation

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