1Q32
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase
Summary for 1Q32
Entry DOI | 10.2210/pdb1q32/pdb |
Descriptor | tyrosyl-DNA phosphodiesterase (2 entities in total) |
Functional Keywords | tyrosyl-dna phosphodiesterase; tdp; dna repair, replication, transcription, hydrolase |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Cellular location | Nucleus: P38319 |
Total number of polymer chains | 4 |
Total formula weight | 249656.33 |
Authors | He, X.,Babaoglu, K.,Price, A.,Nitiss, K.C.,Nitiss, J.L.,White, S.W. (deposition date: 2003-07-28, release date: 2004-09-07, Last modification date: 2024-02-14) |
Primary citation | He, X.,van Waardenburg, R.C.,Babaoglu, K.,Price, A.C.,Nitiss, K.C.,Nitiss, J.L.,Bjornsti, M.A.,White, S.W. Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison J.Mol.Biol., 372:1070-1081, 2007 Cited by PubMed: 17707402DOI: 10.1016/j.jmb.2007.07.055 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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