1Q2X

Crystal Structure of the E243D Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae bound with substrate aspartate semialdehyde

Summary for 1Q2X

• Entry DOI: 10.2210/pdb1q2x/pdb
• Related: 1NWC 1NWH
• Descriptor: Aspartate-semialdehyde dehydrogenase (2 entities in total)
• Functional Keywords: enzyme, aspartate semialdehyde dehydrogenase, tetrahedral intermediate, oxidoreductase
• Biological source: Haemophilus influenzae Rd
• Total number of polymer chains: 2
• Total formula weight: 81373.62

Authors

Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. (deposition date: 2003-07-26, release date: 2004-07-27, Last modification date: 2023-08-16)

• Primary citation: Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E.; The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.; Acta Crystallogr.,Sect.D, 60:1388-1395, 2004; PubMed: 15272161; DOI: 10.1107/S0907444904012971

Experimental method

X-RAY DIFFRACTION (2.05 Å)