8E79
 
 | | Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2022-08-23 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
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8DXO
 | | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2 | | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | | 登録日 | 2022-08-02 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
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8E95
 | | Mycobacterium tuberculosis RNAP elongation complex | | 分子名称: | DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | | 登録日 | 2022-08-26 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
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7LUN
 | | Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980 | | 分子名称: | 7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one, CHLORIDE ION, GLYCEROL, ... | | 著者 | Dorsey, B.W, Swinger, K.K, Schenkel, L.B, Church, W.D, Perl, N.R, Vasbinder, M.M, Wigle, T.J, Kuntz, K.W. | | 登録日 | 2021-02-22 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Chembiochem, 22, 2021
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2IJ3
 | | Structure of the A264H mutant of cytochrome P450 BM3 | | 分子名称: | Cytochrome P450 BM3, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Toogood, H.S, Leys, D. | | 登録日 | 2006-09-29 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
J.Biol.Chem., 282, 2007
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6UU7
 | | E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes) | | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Zuo, Y, De, S, Steitz, T.A. | | 登録日 | 2019-10-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
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6VBV
 | | Structure of the bovine BBSome:ARL6:GTP complex | | 分子名称: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | | 著者 | Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. | | 登録日 | 2019-12-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
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8KHP
 | | CULLIN3-KLHL22-RBX1 E3 ligase | | 分子名称: | Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch-like protein 22 | | 著者 | Su, M.-Y, Su, M.-Y. | | 登録日 | 2023-08-22 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme.
Structure, 31, 2023
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8EBU
 | | XPC release from Core7-XPA-DNA (Cy5) | | 分子名称: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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6VDK
 | | CryoEM structure of HIV-1 conserved Intasome Core | | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | | 著者 | Li, M, Chen, X, Craigie, R. | | 登録日 | 2019-12-27 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.
J.Mol.Biol., 432, 2020
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8EBV
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8EBS
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7M0R
 | | Cryo-EM structure of the Sema3A/PlexinA4/Neuropilin 1 complex | | 分子名称: | CALCIUM ION, Neuropilin-1, Plexin-A4, ... | | 著者 | Lu, D, Shang, G, He, X, Bai, X, Zhang, X. | | 登録日 | 2021-03-11 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex.
Nat Commun, 12, 2021
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8EBT
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8EBY
 | | XPC release from Core7-XPA-DNA (AP) | | 分子名称: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBW
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7DPM
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | | 登録日 | 2020-12-20 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | | 主引用文献 | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV.
Mabs, 13, 2021
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8EBX
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6F1E
 | | Crystal structure of olive flounder [Paralichthys olivaceus] interferon gamma at 2.3 Angstrom resolution | | 分子名称: | Interferon gamma | | 著者 | Kolenko, P, Kolarova, L, Zahradnik, J, Schneider, B. | | 登録日 | 2017-11-21 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | | 主引用文献 | Interferons type II and their receptors R1 and R2 in fish species: Evolution, structure, and function.
Fish Shellfish Immunol., 79, 2018
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6V7I
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6V7Z
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8DN7
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6UQO
 | | ClpA/ClpP Engaged State bound to RepA-GFP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp endopeptidase proteolytic subunit ClpP, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | 著者 | Lopez, K.L, Rizo, A.N, Southworth, D.R. | | 登録日 | 2019-10-21 | | 公開日 | 2020-04-22 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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6VBE
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7LYE
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