6V7I

Structure of KPC-2 bound to Vaborbactam at 1.25 A

Summary for 6V7I

Entry DOI	10.2210/pdb6v7i/pdb
Descriptor	Carbapenem-hydrolyzing beta-lactamase KPC, Vaborbactam, SULFATE ION, ... (5 entities in total)
Functional Keywords	carbapenemase, boronate, beta-lactamase, inhibitor, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	31580.11
Authors	Pemberton, O.A.,Chen, Y. (deposition date: 2019-12-08, release date: 2020-08-12, Last modification date: 2023-10-11)
Primary citation	Pemberton, O.A.,Tsivkovski, R.,Totrov, M.,Lomovskaya, O.,Chen, Y. Structural Basis and Binding Kinetics of Vaborbactam in Class A beta-Lactamase Inhibition. Antimicrob.Agents Chemother., 64:-, 2020 Cited by PubMed: 32778546 DOI: 10.1128/AAC.00398-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation