6V7I
Structure of KPC-2 bound to Vaborbactam at 1.25 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 290 | 30806.6 | 1 | UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
| 2 | B (A) | Vaborbactam | non-polymer | 297.1 | 1 | Chemie (4D6) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 25 - 295 (UniProt: Q9F663)
| PDB | External Database | Details |
|---|---|---|
| Met 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ser 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| Ser 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Gly 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Val 18 | - | expression tag |
| Pro 19 | - | expression tag |
| Arg 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Ser 22 | - | expression tag |
| His 23 | - | expression tag |
| Met 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30806.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 773.5 | |
| All* | Total formula weight | 31580.1 |
