PDB: 37997 件ウェブページステータス検索Chemie searchBIRD

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8TOW	Structure of a mutated photosystem II complex reveals perturbation of the oxygen-evolving complex 分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Flesher, D.A, Liu, J, Wang, J, Gisriel, C.J, Yang, K.R, Batista, V.S, Debus, R.J, Brudvig, G.W. 登録日 2023-08-04 公開日 2024-06-19 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.14 Å) 主引用文献 Mutation-induced shift of the photosystem II active site reveals insight into conserved water channels. J.Biol.Chem., 300, 2024
6NCW	Crystal structure of a GH2 beta-galacturonidase from Eisenbergiella tayi bound to glycerol 分子名称: Beta-galacturonidase, CHLORIDE ION, GLYCEROL 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-12-12 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
5LB6	HIF prolyl hydroxylase 2 (PHD2/EGLN1) R371H variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: Egl nine homolog 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5LBE	HIF prolyl hydroxylase 2 (PHD2/EGLN1) G294E variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/FG2216) 分子名称: BICARBONATE ION, Egl nine homolog 1, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
9BWI	Crystal structure of cellulose oxidative enzyme in acidic pH with glycerol 分子名称: COPPER (II) ION, Cellulose oxidative enzyme, GLYCEROL 著者 Morais, M.A.B, Santos, C.A, Araujo, E.A, Santos, C.R, Morao, L.G, Motta, M.L, Murakami, M.T. 登録日 2024-05-21 公開日 2024-12-11 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A metagenomic 'dark matter' enzyme catalyses oxidative cellulose conversion. Nature, 639, 2025
7N03	Crystal structure of MTH1 in complex with compound 31 分子名称: 4-anilino-6-(hexylamino)-N-methylquinoline-3-carboxamide, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Eron, S.J. 登録日 2021-05-24 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Development of an AchillesTAG degradation system and its application to control CAR-T activity Curr Res Chem Biol, 1, 2021
6NCI	Crystal structure of CDP-Chase: Vector data collection 分子名称: D-ribose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Miller, M.S, Shi, W, Gabelli, S.B. 登録日 2018-12-11 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
5LBZ	Structure of the human quinone reductase 2 (NQO2) in complex with pacritinib 分子名称: 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Schneider, S, Medard, G, Kuster, B. 登録日 2016-06-17 公開日 2017-11-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The target landscape of clinical kinase drugs. Science, 358, 2017
7N13	Crystal structure of MTH1 in complex with compound 32 分子名称: 4-anilino-6-[4-(butylcarbamoyl)-3-fluorophenyl]-N-cyclopropyl-7-fluoroquinoline-3-carboxamide, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Eron, S.J. 登録日 2021-05-26 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Development of an AchillesTAG degradation system and its application to control CAR-T activity Curr Res Chem Biol, 1, 2021
5KZW	Crystal structure of human GAA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Deming, D.T, Garman, S.C. 登録日 2016-07-25 公開日 2017-07-26 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of human GAA: structural basis of Pompe disease To be published
9C4E	Structure of endogenous DPYSL2 from rat model of Alzheimer's disease 分子名称: Dihydropyrimidinase-related protein 2 著者 Khalili Samani, E, Keszei, A.F.A, Mazhab-Jafari, M.T. 登録日 2024-06-04 公開日 2024-12-11 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Unveiling the structural proteome of an Alzheimer's disease rat brain model. Structure, 33, 2025
9C86	Structure of endogenous asymmetric DPYSL2 from rat model of Alzheimer's disease 分子名称: Dihydropyrimidinase-related protein 2, GLYCINE 著者 Khalili Samani, E, Keszei, A.F.A, Mazhab-Jafari, M.T. 登録日 2024-06-12 公開日 2024-12-11 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Unveiling the structural proteome of an Alzheimer's disease rat brain model. Structure, 33, 2025
8TBA	Crystal structure of Helicobacter pylori glutamate racemase bound to D-glutamate and a crystallographic artifact 分子名称: (2M)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-[5-(4-methylphenyl)-1,3-oxazol-2-yl]benzamide, D-GLUTAMIC ACID, DIMETHYL SULFOXIDE, ... 著者 Propp, J, Spies, M.A. 登録日 2023-06-28 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of Helicobacter pylori glutamate racemase bound to D-glutamate and a likely crystallographic artifact To Be Published
4LDY	Crystal structure of the DNA binding domain of the G245A mutant of arabidopsis thaliana auxin reponse factor 1 分子名称: Auxin response factor 1, CHLORIDE ION 著者 Boer, D.R, Freire-Rios, A, van den Berg, W.M.A, Weijers, D, Coll, M. 登録日 2013-06-25 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Cell(Cambridge,Mass.), 156, 2014
6NI3	B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex 分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. 登録日 2018-12-26 公開日 2019-11-20 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
5KLK	Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169D in complex with NAD+ and 2-hydroxymuconate-6-semialdehyde 分子名称: (2E,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid, 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. 登録日 2016-06-24 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.006 Å) 主引用文献 A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism. J.Biol.Chem., 291, 2016
9BZ0	Structure of an STK19-containing TC-NER complex 分子名称: DET1- and DDB1-associated protein 1, DNA (35-MER), DNA (49-MER), ... 著者 Mevissen, T.E.T, Kuemmecke, M, Farnung, L, Walter, J.C. 登録日 2024-05-24 公開日 2024-12-25 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (1.9 Å) 主引用文献 STK19 positions TFIIH for cell-free transcription-coupled DNA repair. Cell, 187, 2024
5L94	The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
5LAG	Room temperature X-ray diffraction of tetragonal HEWL with 1M of uridine. Second data set (0.62 MGy) 分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C 著者 Castellvi, A, Juanhuix, J. 登録日 2016-06-14 公開日 2016-12-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Uridine as a new scavenger for synchrotron-based structural biology techniques. J Synchrotron Radiat, 24, 2017
8U19	Crystal structure of SyoA bound to syringol 分子名称: 2,6-dimethoxyphenol, Cytochrome P450, MAGNESIUM ION, ... 著者 Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. 登録日 2023-08-31 公開日 2024-07-24 最終更新日 2025-03-19 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Structural insights into S-lignin O-demethylation via a rare class of heme peroxygenase enzymes. Nat Commun, 16, 2025
9CGP	RyR1 disease mutant Y523S with FKBP12.6, nanodisc and inhibitor dantrolene in the absence of calcium with refined P1 domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Dantrolene, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Iyer, K.A, Samso, M. 登録日 2024-06-30 公開日 2024-12-11 最終更新日 2025-02-19 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Dantrolene inhibition of ryanodine receptor 1 carrying the severe malignant hyperthermia mutation Y522S visualized by cryo-EM. Structure, 33, 2025
5LBT	Structure of the human quinone reductase 2 (NQO2) in complex with imiquimod 分子名称: 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Schneider, S, Gross, O. 登録日 2016-06-17 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Imiquimod Inhibits Mitochondrial Complex I and Induces K+ efflux-independent Nlrp3 Inflammasome Activation via Nek7 To Be Published
5LC5	Structure of mammalian respiratory Complex I, class2 分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Vinothkumar, K.R, Zhu, J, Hirst, J. 登録日 2016-06-19 公開日 2016-09-07 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Structure of mammalian respiratory complex I. Nature, 536, 2016
8U09	Crystal structure of substrate-free SyoA 分子名称: ACETATE ION, Cytochrome P450, GLYCEROL, ... 著者 Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. 登録日 2023-08-28 公開日 2024-07-24 最終更新日 2025-03-19 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural insights into S-lignin O-demethylation via a rare class of heme peroxygenase enzymes. Nat Commun, 16, 2025
9CL1	Particulate methane monooxygenase in 0.02% DDM 分子名称: COPPER (II) ION, Methane monooxygenase, C subunit, ... 著者 Tucci, F.J, Rosenzweig, A.C. 登録日 2024-07-10 公開日 2025-01-08 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structures of methane and ammonia monooxygenases in native membranes. Proc.Natl.Acad.Sci.USA, 122, 2025

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