PDB: 35415 件ウェブページステータス検索Chemie searchBIRD

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4NLE	Crystal structure of apo Adenylosuccinate Lyase from Mycobacterium smegmatis 分子名称: Adenylosuccinate lyase 著者 Banerjee, S, Murthy, M.R.N. 登録日 2013-11-14 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme. Febs J., 281, 2014
6WJG	PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma 分子名称: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit 著者 Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. 登録日 2020-04-13 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
4NFO	Crystal Structure Analysis of the 16mer GCAGACUUAAGUCUGC 分子名称: GCAGACUUAAGUCUGC, SPERMINE 著者 Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. 登録日 2013-10-31 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA. Acs Chem.Biol., 9, 2014
6WJY	HUMAN IDO1 IN COMPLEX WITH COMPOUND 4-A 分子名称: 3-chloro-N-(3-{(2S)-1-[(4-fluorophenyl)amino]-1-oxopropan-2-yl}bicyclo[1.1.1]pentan-1-yl)benzamide, Indoleamine 2,3-dioxygenase 1 著者 Lesburg, C.A, Lammens, A, Neumann, L. 登録日 2020-04-14 公開日 2020-08-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors. Acs Med.Chem.Lett., 11, 2020
8K6B	Crystal structure of SARS-CoV-2 3CLpro M49K/M165V mutant 分子名称: 3C-like proteinase nsp5 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
8K6A	Crystal structure of SARS-CoV-2 3CLpro S301P mutant 分子名称: 3C-like proteinase nsp5 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
8FA2	Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex 分子名称: Scaffolded Spike protein S2' HR1, Spike protein S2' 42G 著者 Yang, K, Brunger, A.T. 登録日 2022-11-25 公開日 2023-03-29 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proc.Natl.Acad.Sci.USA, 120, 2023
6WKW	EM structure of CtBP2 with a minimal dehydrogenase domain of CtBP2 分子名称: C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Jecrois, A.M. 登録日 2020-04-17 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of CtBP2 confirms tetrameric architecture. Structure, 29, 2021
8FA1	Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation 分子名称: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2 著者 Yang, K, Brunger, A.T. 登録日 2022-11-25 公開日 2023-03-29 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proc.Natl.Acad.Sci.USA, 120, 2023
8K68	Crystal structure of SARS-CoV-2 3CLpro M49K mutant 分子名称: 3C-like proteinase nsp5 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
5D9V	Crystal structure of oxidized dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Dehydroascorbate reductase 著者 Do, H, Lee, J.H. 登録日 2015-08-19 公開日 2016-02-03 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica Sci Rep, 6, 2016
6WUM	Mitochondrial SAM complex - dimer 2 in detergent 分子名称: Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein 著者 Ni, X, Botos, I, Diederichs, K. 登録日 2020-05-04 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis. Nat Commun, 11, 2020
8K67	Crystal structure of SARS-CoV-2 3CLpro M165V mutant 分子名称: 3C-like proteinase nsp5 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
1G6V	Complex of the camelid heavy-chain antibody fragment CAB-CA05 with bovine carbonic anhydrase 分子名称: ANTIBODY HEAVY CHAIN, CARBONIC ANHYDRASE, ZINC ION 著者 Desmyter, A, Decanniere, K, Muyldermans, S, Wyns, L. 登録日 2000-11-08 公開日 2000-11-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody. J.Biol.Chem., 276, 2001
6WYC	Crystal Structure of Chlamydia trachomatis Glyceraldehyde 3-phosphate dehydrogenase 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Schormann, N, Chattopadhyay, D. 登録日 2020-05-12 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding. Protein Sci., 29, 2020
8K6C	Crystal structure of SARS-CoV-2 3CLpro M49K/S301P mutant 分子名称: 3C-like proteinase nsp5 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
1GFW	THE 2.8 ANGSTROM CRYSTAL STRUCTURE OF CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR. 分子名称: 1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE, CASPASE-3 (APOPAIN, P10), ... 著者 Concha, N.O, Janson, C.A. 登録日 2000-06-16 公開日 2000-06-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J.Biol.Chem., 275, 2000
8K6D	Crystal structure of SARS-CoV-2 3CLpro M49K/S301P mutant in complex with WU-04 分子名称: 3C-like proteinase nsp5, ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide 著者 Zhang, L.J, Hu, Q. 登録日 2023-07-25 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10, 2024
6WTI	The Cryo-EM structure of the ubiquinol oxidase from Escherichia coli 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome o ubiquinol oxidase, ... 著者 Su, C.-C. 登録日 2020-05-02 公開日 2021-01-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.38 Å) 主引用文献 A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins. Nat.Methods, 18, 2021
3BHM	Crystal structure of human Carbonyl Reductase 1 in complex with S-hydroxymethylglutathione 分子名称: 2-AMINO-4-[1-CARBOXYMETHYL-CARBAMOYL)-2-HYDROXYMETHYLSULFANYL-ETHYLCARBAMOYL]-BUTYRIC ACID, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, Carbonyl reductase [NADPH] 1, ... 著者 Bateman, R.L, Rauh, D, Shokat, K.M. 登録日 2007-11-28 公開日 2008-10-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Human carbonyl reductase 1 is an s-nitrosoglutathione reductase J.Biol.Chem., 283, 2008
6WUH	Mitochondrial SAM complex in lipid nanodiscs 分子名称: Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein 著者 Ni, X, Botos, I, Diederichs, K. 登録日 2020-05-04 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis. Nat Commun, 11, 2020
6WV5	Human VKOR C43S mutant with vitamin K1 epoxide 分子名称: (2R,3R)-2-hydroxy-3-methyl-2-[(2E,7S)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-2,3-dihydronaphthalene-1,4-dione, Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein 著者 Liu, S, Sukumar, N, Li, W. 登録日 2020-05-05 公開日 2020-11-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
4NUU	Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC) 分子名称: Duffy antigen/chemokine receptor, Duffy receptor 著者 Tolia, N.H. 登録日 2013-12-04 公開日 2014-02-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC. Plos Pathog., 10, 2014
8FKB	X-ray crystal structure of CYP124A1 from Mycobacterium Marinum bound to Farnesol 分子名称: (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, Cytochrome P450 124A1, DI(HYDROXYETHYL)ETHER, ... 著者 Ghith, A, Bruning, J.B, Bell, S.G. 登録日 2022-12-21 公開日 2023-03-29 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 737, 2023
5CR1	Crystal structure of TTR/resveratrol/T4 complex 分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, RESVERATROL, Transthyretin 著者 Zanotti, G, Florio, P, Folli, C, Cianci, M, Del Rio, D, Berni, R. 登録日 2015-07-22 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.545 Å) 主引用文献 Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites. J.Biol.Chem., 290, 2015

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