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7WYV
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Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mM Mg2+
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
登録日2022-02-16
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WYZ
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Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with ouabain
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
登録日2022-02-16
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WZ0
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BU of 7wz0 by Molmil
Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with ouabain
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
登録日2022-02-16
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GTT
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BU of 8gtt by Molmil
Cryo-EM structure of human Pannexin1 resembling Pannexin2 pore with W74R/R75Dmutations
分子名称: Pannexin-1
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
6WOU
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BU of 6wou by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
登録日2020-04-25
公開日2020-08-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
8GTS
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CryoEM structure of human Pannexin1 with R217H congenital mutation.
分子名称: Pannexin-1
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
4UIJ
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BU of 4uij by Molmil
Crystal structure of the BTB domain of KCTD13
分子名称: BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1, CHLORIDE ION
著者Pinkas, D.M, Sanvitale, C.E, Sorell, F.J, Solcan, N, Goubin, S, Canning, P, Williams, E, Chaikuad, A, Dixon Clarke, S.E, Tallant, C, Fonseca, M, Chalk, R, Doutch, J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2015-03-30
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017
2VE3
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BU of 2ve3 by Molmil
Retinoic acid bound cyanobacterial CYP120A1
分子名称: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120, RETINOIC ACID
著者Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I.
登録日2007-10-15
公開日2008-04-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1.
Biochemistry, 47, 2008
8GTR
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BU of 8gtr by Molmil
CryoEM structure of human Pannexin isoform 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
登録日2021-03-18
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
5GHD
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BU of 5ghd by Molmil
SOLUTION STRUCTURE OF LYS39 ACETYLATED HUMAN SUMO1
分子名称: Small ubiquitin-related modifier 1
著者Naik, M.T, Naik, N, Shih, H, Huang, T.
登録日2016-06-19
公開日2017-06-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structures of Human Sumo
To Be Published
1WM8
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BU of 1wm8 by Molmil
Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures
分子名称: Neurotoxin BmP03
著者Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X.
登録日2004-07-05
公開日2004-07-27
最終更新日2018-04-18
実験手法SOLUTION NMR
主引用文献Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch
Acta Chim.Sinica, 58, 2000
3WGV
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BU of 3wgv by Molmil
Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C.
登録日2013-08-09
公開日2013-10-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state
Nature, 502, 2013
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
分子名称: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
7VUO
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BU of 7vuo by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
分子名称: CALCIUM ION, Calmodulin-1, Kv7.1
著者Chen, L.
登録日2021-11-03
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
5CFB
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BU of 5cfb by Molmil
Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-3,Glycine receptor subunit alpha-3, ...
著者Shaffer, P.L, Huang, X, Chen, H.
登録日2015-07-08
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal structure of human glycine receptor-alpha 3 bound to antagonist strychnine.
Nature, 526, 2015
2K7M
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BU of 2k7m by Molmil
Structure of the Connexin40 Carboxyl terminal Domain
分子名称: Gap junction alpha-5 protein
著者Bouvier, D, Spagnol, G, Kieken, F, Vitrac, H, Kellezi, A, Forge, V.
登録日2008-08-14
公開日2009-07-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains.
J.Biol.Chem., 284, 2009
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
分子名称: Venom polypeptide
著者Agwa, A.J, Schroeder, C.
登録日2019-07-25
公開日2020-01-22
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6PX8
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BU of 6px8 by Molmil
Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
分子名称: Venom polypeptide
著者Agwa, A.J, Schroeder, C.
登録日2019-07-25
公開日2020-01-22
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
2JP3
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BU of 2jp3 by Molmil
Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles
分子名称: FXYD domain-containing ion transport regulator 4
著者Franzin, C.M, Teriete, P, Marassi, F.M.
登録日2007-04-18
公開日2008-03-04
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structural similarity of a membrane protein in micelles and membranes
J.Am.Chem.Soc., 129, 2007
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
分子名称: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
登録日2019-08-03
公開日2019-09-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
2JUL
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BU of 2jul by Molmil
NMR Structure of DREAM
分子名称: CALCIUM ION, Calsenilin
著者Ames, J.
登録日2007-08-30
公開日2008-04-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization.
Biochemistry, 47, 2008
5B7A
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BU of 5b7a by Molmil
SOLUTION STRUCTURE OF LYS37 ACETYLATED HUMAN SUMO1
分子名称: Small ubiquitin-related modifier 1
著者Naik, M.T, Naik, N, Shih, H, Huang, T.
登録日2016-06-05
公開日2017-06-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structures Of Human Sumo
To Be Published
2YGG
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BU of 2ygg by Molmil
Complex of CaMBR and CaM
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
著者Koester, S, Yildiz, O.
登録日2011-04-15
公開日2011-09-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.227 Å)
主引用文献Structure of Human Na+/H+ Exchanger Nhe1 Regulatory Region in Complex with Cam and Ca2+
J.Biol.Chem., 286, 2011
7T64
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Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2021-12-13
公開日2022-07-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022

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