8VLJ
 
 | | Crystal structure of the cacodylate-bound yeast cytosine deaminase (closed form) | | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, Cytosine deaminase, ... | | 著者 | Picard, M.-E, Grenier, J, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Compensatory mutations potentiate constructive neutral evolution by gene duplication
Science, 2024
|
|
8VLK
 | | Crystal structure of the yeast cytosine deaminase containing both open and closed active sites | | 分子名称: | 1,2-ETHANEDIOL, Cytosine deaminase, SULFATE ION, ... | | 著者 | Picard, M.-E, Grenier, J, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Compensatory mutations potentiate constructive neutral evolution by gene duplication
Science, 2024
|
|
6M3U
 | |
8VLM
 | | Crystal structure of the yeast cytosine deaminase (yCD) E64V-M100W heterodimer | | 分子名称: | 1,2-ETHANEDIOL, Cytosine deaminase, ZINC ION | | 著者 | Picard, M.-E, Grenier, G, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Compensatory mutations potentiate constructive neutral evolution by gene duplication
Science, 2024
|
|
8TN9
 | | Structural architecture of the acidic region of the B domain of coagulation factor V | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor V | | 著者 | Mohammed, B.M, Basore, K, Summers, B, Pelc, L.A, Di Cera, E. | | 登録日 | 2023-08-01 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural architecture of the acidic region of the B domain of coagulation factor V.
J.Thromb.Haemost., 22, 2024
|
|
5F7Y
 | | Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group A type-1 hexasaccharide | | 分子名称: | Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H. | | 登録日 | 2015-12-08 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
|
|
5WTF
 | | Cryo-EM structure for Hepatitis A virus empty particle | | 分子名称: | VP0, VP1, VP3 | | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | | 登録日 | 2016-12-11 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7L5C
 | | Structure of copper bound MEMO1 | | 分子名称: | 1,2-ETHANEDIOL, COPPER (I) ION, GLYCEROL, ... | | 著者 | Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y. | | 登録日 | 2020-12-21 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | MEMO1 binds iron and modulates iron homeostasis in cancer cells.
Elife, 13, 2024
|
|
5NZP
 | | Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-Hydroxybenzisoxazole | | 分子名称: | 1,2-benzoxazol-3-ol, D-3-phosphoglycerate dehydrogenase | | 著者 | Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. | | 登録日 | 2017-05-14 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.
Oncotarget, 9, 2018
|
|
5NW4
 | | Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2 | | 分子名称: | Arp1, Arp11, BICD2N, ... | | 著者 | Zhang, K, Foster, H.E, Carter, A.P. | | 登録日 | 2017-05-05 | | 公開日 | 2017-08-02 | | 最終更新日 | 2018-11-21 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
|
|
7KRG
 | |
6T0J
 | | Crystal structure of CYP124 in complex with SQ109 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GLYCEROL, ... | | 著者 | Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. | | 登録日 | 2019-10-03 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450.
Int J Mol Sci, 21, 2020
|
|
6MMR
 | | Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, 3 millimolar EDTA, and at pH 7.4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | | 著者 | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | | 登録日 | 2018-10-01 | | 公開日 | 2018-11-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.13 Å) | | 主引用文献 | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Cell, 175, 2018
|
|
3IQT
 | | Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073. | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Signal transduction histidine-protein kinase barA | | 著者 | Cuff, M.E, Rakowski, E, Kim, Y, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-08-20 | | 公開日 | 2009-09-22 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.
TO BE PUBLISHED
|
|
5LNS
 | | Crystal structure of Arabidopsis thaliana Pdx1-R5P complex | | 分子名称: | PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, RIBULOSE-5-PHOSPHATE | | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | | 登録日 | 2016-08-06 | | 公開日 | 2017-01-18 | | 最終更新日 | 2017-02-22 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
Nat. Chem. Biol., 13, 2017
|
|
5LOJ
 | |
5AD1
 | | A complex of the synthetic siderophore analogue Fe(III)-8-LICAM with the CeuE periplasmic protein from Campylobacter jejuni | | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-OCTANE-1,8-DIYLBIS(2,3-DIHYDROXYBENZAMIDE) | | 著者 | Blagova, E, Hughes, A, Moroz, O.V, Raines, D.J, Wilde, E.J, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2015-08-19 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
|
|
1C05
 | | SOLUTION STRUCTURE OF RIBOSOMAL PROTEIN S4 DELTA 41, REFINED WITH DIPOLAR COUPLINGS (MINIMIZED AVERAGE STRUCTURE) | | 分子名称: | RIBOSOMAL PROTEIN S4 DELTA 41 | | 著者 | Markus, M.A, Gerstner, R.B, Draper, D.E, Torchia, D.A. | | 登録日 | 1999-07-14 | | 公開日 | 1999-09-29 | | 最終更新日 | 2024-04-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refining the overall structure and subdomain orientation of ribosomal protein S4 delta41 with dipolar couplings measured by NMR in uniaxial liquid crystalline phases.
J.Mol.Biol., 292, 1999
|
|
6SPO
 | | Structure of the Escherichia coli methionyl-tRNA synthetase complexed with methionine | | 分子名称: | CITRIC ACID, GLYCEROL, METHIONINE, ... | | 著者 | Nigro, G, Schmitt, E, Mechulam, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Use of beta3-methionine as an amino acid substrate of Escherichia coli methionyl-tRNA synthetase.
J.Struct.Biol., 209, 2020
|
|
6MMB
 | | Diheteromeric NMDA receptor GluN1/GluN2A in the 'Super-Splayed' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | | 著者 | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | | 登録日 | 2018-09-30 | | 公開日 | 2018-11-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (12.7 Å) | | 主引用文献 | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Cell, 175, 2018
|
|
2VNU
 | | Crystal structure of Sc Rrp44 | | 分子名称: | 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP)-3', EXOSOME COMPLEX EXONUCLEASE RRP44, MAGNESIUM ION, ... | | 著者 | Lorentzen, E, Basquin, J, Conti, E. | | 登録日 | 2008-02-07 | | 公開日 | 2008-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the Rnase II Nuclease Family
Mol.Cell, 29, 2008
|
|
6AWN
 | |
1YRO
 | | Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | | 著者 | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | | 登録日 | 2005-02-04 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I
Biochemistry, 44, 2005
|
|
5LMC
 | | Oxidized flavodiiron core of Escherichia coli flavorubredoxin, including the Fe-4SG atoms from its rubredoxin domain | | 分子名称: | ACETIC ACID, Anaerobic nitric oxide reductase flavorubredoxin, CACODYLATE ION, ... | | 著者 | Romao, C.V, Borges, P.T, Vicente, J.B, Carrondo, M.A, Teixeira, M, Frazao, C. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of Escherichia coli Flavodiiron Nitric Oxide Reductase.
J.Mol.Biol., 428, 2016
|
|
5SV1
 | | Structure of the ExbB/ExbD complex from E. coli at pH 4.5 | | 分子名称: | Biopolymer transport protein ExbB, Biopolymer transport protein ExbD, MERCURY (II) ION | | 著者 | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | | 登録日 | 2016-08-04 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural insight into the role of the Ton complex in energy transduction.
Nature, 538, 2016
|
|
