6AWN
X-ray structure of the S439T human serotonin transporter complexed with paroxetine at the central site
Summary for 6AWN
| Entry DOI | 10.2210/pdb6awn/pdb |
| Related | 5I66 5I6Z 5I71 5I73 5I74 5I75 |
| Descriptor | Sodium-dependent serotonin transporter, 8B6 antibody FAB heavy chain, 8B6 antibody FAB light chain, ... (9 entities in total) |
| Functional Keywords | neurotransmitter transporter, antidepressant, transport protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 112003.12 |
| Authors | Coleman, J.A.,Gouaux, E. (deposition date: 2017-09-06, release date: 2017-10-25, Last modification date: 2023-10-04) |
| Primary citation | Coleman, J.A.,Gouaux, E. Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25:170-175, 2018 Cited by PubMed: 29379174DOI: 10.1038/s41594-018-0026-8 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.62 Å) |
Structure validation
Download full validation report
