PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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5ORO	Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment 分子名称: 3-(4-chlorophenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. 登録日 2017-08-16 公開日 2017-11-01 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chem. Biol., 12, 2017
5ORR	Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment 分子名称: 4-[4-(trifluoromethyl)phenyl]-1,2,3-thiadiazol-5-amine, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. 登録日 2017-08-16 公開日 2017-11-01 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chem. Biol., 12, 2017
1K90	Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP 分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CALMODULIN, ... 著者 Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J. 登録日 2001-10-26 公開日 2002-01-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature, 415, 2002
4OKH	Crystal structure of calpain-3 penta-EF-hand domain 分子名称: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, CALCIUM ION, Calpain-3 著者 Karunan Partha, S, Ravulapalli, R, Campbell, R.L, Allingham, J.S, Davies, P.L. 登録日 2014-01-22 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand. Febs J., 281, 2014
3BQ7	SAM domain of Diacylglycerol Kinase delta1 (E35G) 分子名称: Diacylglycerol kinase delta 著者 Knight, M.J, Bowie, J.U, Sawaya, M.R. 登録日 2007-12-19 公開日 2008-03-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase delta1 Structure, 16, 2008
4OCY	Fab for methotrexate (unbound apo) 分子名称: Fab ADD058 Heavy Chain, Fab ADD058 Light Chain 著者 Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. 登録日 2014-01-09 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
2Z51	Crystal structure of Arabidopsis CnfU involved in iron-sulfur cluster biosynthesis 分子名称: MAGNESIUM ION, NifU-like protein 2, chloroplast 著者 Yabe, T, Yamashita, E, Nakai, M. 登録日 2007-06-26 公開日 2008-07-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Analysis of Arabidopsis CnfU Protein: An Iron-Sulfur Cluster Biosynthetic Scaffold in Chloroplasts. J.Mol.Biol., 2008
4O4S	Crystal structure of phycobiliprotein lyase CpcT complexed with phycocyanobilin (PCB) 分子名称: PHYCOCYANOBILIN, Phycocyanobilin lyase CpcT 著者 Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. 登録日 2013-12-19 公開日 2014-08-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and Mechanism of the Phycobiliprotein Lyase CpcT. J.Biol.Chem., 289, 2014
3EKH	Calcium-saturated GCaMP2 T116V/K378W mutant monomer 分子名称: CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... 著者 Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. 登録日 2008-09-19 公開日 2008-12-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
1KZ5	Solution structure of the third helix of Antennapedia homeodomain derivatives (RQIKIWFRKWKK) 分子名称: Antennapedia protein 著者 Czajlik, A, Mesko, E, Penke, B, Perczel, A. 登録日 2002-02-06 公開日 2002-02-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives. J.Pept.Sci., 8, 2002
4O4O	Crystal structure of phycobiliprotein lyase CpcT 分子名称: MAGNESIUM ION, Phycocyanobilin lyase CpcT 著者 Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. 登録日 2013-12-19 公開日 2014-08-06 最終更新日 2014-10-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure and Mechanism of the Phycobiliprotein Lyase CpcT. J.Biol.Chem., 289, 2014
2PHA	Crystal structure of native, unliganded human arginase at 1.90 resolution 分子名称: Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Pique, M.E, Christianson, D.W. 登録日 2007-04-10 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster. J.Am.Chem.Soc., 129, 2007
4LQK	Structure of the vaccinia virus NF- B antagonist A46 分子名称: BROMIDE ION, Protein A46, SODIUM ION 著者 Grishkovskaya, I, Fedosyuk, S, Skern, T, Djinovic-Carugo, K. 登録日 2013-07-18 公開日 2013-12-25 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Characterization and Structure of the Vaccinia Virus NF-kappa B Antagonist A46. J.Biol.Chem., 289, 2014
4HEX	A novel conformation of calmodulin 分子名称: CALCIUM ION, Calmodulin, ZINC ION 著者 Kumar, V, Chichili, V.P.R, Sivaraman, J. 登録日 2012-10-04 公開日 2013-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 A novel trans conformation of ligand-free calmodulin Plos One, 8, 2013
4M0Q	Ebola virus VP24 structure 分子名称: Membrane-associated protein VP24 著者 Xu, W, Leung, D.W, Borek, D, Amarasinghe, G.K. 登録日 2013-08-01 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.921 Å) 主引用文献 The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway. Cell Rep, 6, 2014
3AJ2	The structure of AxCeSD octamer (C-terminal HIS-tag) from Acetobacter xylinum 分子名称: Cellulose synthase operon protein D 著者 Hu, S.Q, Tajima, K, Zhou, Y, Tanaka, I, Yao, M. 登録日 2010-05-20 公開日 2010-10-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of bacterial cellulose synthase subunit D octamer with four inner passageways Proc.Natl.Acad.Sci.USA, 107, 2010
3LI0	Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 分子名称: 1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-01-23 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
4MEM	Crystal Structure of the rat USP11 DUSP-UBL domains 分子名称: Ubiquitin carboxyl-terminal hydrolase 11 著者 Harper, S, Gratton, H.E, Cornaciu, I, Oberer, M, Scott, D.J, Emsley, J, Dreveny, I. 登録日 2013-08-27 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains. Biochemistry, 53, 2014
4IL1	Crystal Structure of the Rat Calcineurin 分子名称: CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ... 著者 Ye, Q, Faucher, F, Jia, Z. 登録日 2012-12-28 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of calcineurin activation by calmodulin. Cell Signal, 25, 2013
3LB6	The structure of IL-13 in complex with IL-13Ralpha2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Interleukin-13, ... 著者 Lupardus, P.J, Garcia, K.C, Birnbaum, M.E. 登録日 2010-01-07 公開日 2010-03-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure, 18, 2010
1KZ2	Solution structure of the third helix of Antennapedia homeodomain derivative [W6F,W14F] 分子名称: Antennapedia protein 著者 Czajlik, A, Mesko, E, Penke, B, Perczel, A. 登録日 2002-02-06 公開日 2002-02-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives. J.Pept.Sci., 8, 2002
4IH3	2.5 Angstroms X-ray crystal structure of of human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid 分子名称: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, PYRIDINE-2,6-DICARBOXYLIC ACID, ZINC ION 著者 Huo, L, Liu, A. 登録日 2012-12-18 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.493 Å) 主引用文献 Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling. Proteins, 83, 2015
2PEV	Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution exceeds concentration of IDD594. 分子名称: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose reductase, CHLORIDE ION, ... 著者 Petrova, T, Hazemann, I, Cousido, A, Mitschler, A, Ginell, S, Joachimiak, A, Podjarny, A. 登録日 2007-04-03 公開日 2007-04-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins, 80, 2012
4JWL	Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH7.5 分子名称: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide 著者 Hoh, F, Rouhana, J. 登録日 2013-03-27 公開日 2013-10-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors J.Med.Chem., 56, 2013
5ZJI	Structure of photosystem I supercomplex with light-harvesting complexes I and II 分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... 著者 Pan, X.W, Ma, J, Su, X.D, Cao, P, Liu, Z.F, Zhang, X.Z, Li, M. 登録日 2018-03-20 公開日 2018-06-20 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the maize photosystem I supercomplex with light-harvesting complexes I and II. Science, 360, 2018

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