1K90

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP

Summary for 1K90

DescriptorCALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, YTTERBIUM (III) ION, ... (6 entities in total)
Functional Keywordsoedema factor adenylyl cyclase anthrax calmodulin, toxin, lyase-metal binding protein complex, lyase/metal binding protein
Biological sourceBacillus anthracis
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Cellular locationSecreted P40136
Cytoplasm, cytoskeleton, spindle P02593
Total number of polymer chains6
Total molecular weight228829
Authors
Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. (deposition date: 2001-10-26, release date: 2002-01-23, Last modification date: 2011-07-13)
Primary citation
Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J.
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415:396-402, 2002
PubMed: 11807546 (PDB entries with the same primary citation)
DOI: 10.1038/415396a
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.75 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers343.9%5.9%11.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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