4IH3

2.5 Angstroms X-ray crystal structure of of human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid

Summary for 4IH3

• Entry DOI: 10.2210/pdb4ih3/pdb
• Related: 4IFK 4IFO 4IFR 4IG2
• Descriptor: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (4 entities in total)
• Functional Keywords: tim-barrel, decarboxylation, metal-binding, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 226698.94

Authors

Huo, L.,Liu, A. (deposition date: 2012-12-18, release date: 2014-05-21, Last modification date: 2023-09-20)

• Primary citation: Huo, L.,Liu, F.,Iwaki, H.,Li, T.,Hasegawa, Y.,Liu, A.; Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling.; Proteins, 83:178-187, 2015; PubMed: 25392945; DOI: 10.1002/prot.24722

Experimental method

X-RAY DIFFRACTION (2.493 Å)