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3GW7
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BU of 3gw7 by Molmil
Crystal structure of a metal-dependent phosphohydrolase with conserved HD domain (yedJ) from Escherichia coli in complex with nickel ions. Northeast Structural Genomics Consortium Target ER63
分子名称: NICKEL (II) ION, Uncharacterized protein yedJ
著者Forouhar, F, Abashidze, M, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2009-03-31
公開日2009-04-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of a metal-dependent phosphohydrolase with conserved HD domain (yedJ) from Escherichia coli in complex with nickel ions. Northeast Structural Genomics Consortium Target ER63
To be Published
6A2N
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BU of 6a2n by Molmil
Crystal structure of quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum DHFR-TS complexed with BT2, NADPH, and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y.
登録日2018-06-12
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
4UYI
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BU of 4uyi by Molmil
Crystal structure of the BTB domain of human SLX4 (BTBD12)
分子名称: STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4
著者Pinkas, D.M, Sanvitale, C.E, Strain-Damerell, C, Fairhead, M, Wang, D, Tallant, C, Cooper, C.D.O, Sorrell, F.J, Kopec, J, Chaikuad, A, Fitzpatrick, F, Pike, A.C.W, Hozjan, V, Ying, Z, Roos, A.K, Savitsky, P, Bradley, A, Nowak, R, Filippakopoulos, P, Krojer, T, Burgess-Brown, N.A, Marsden, B.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2014-09-01
公開日2014-10-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the Btb Domain of Human Slx4 (Btbd12)
To be Published
130L
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BU of 130l by Molmil
STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Pjura, P, Matthews, B.W.
登録日1993-05-28
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
7DNJ
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BU of 7dnj by Molmil
K63-polyUb MDA5CARDs complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
7DNI
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BU of 7dni by Molmil
MDA5 CARDs-MAVS CARD polyUb complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
131L
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BU of 131l by Molmil
STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Pjura, P, Matthews, B.W.
登録日1993-05-28
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
6XD4
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BU of 6xd4 by Molmil
CDC-like protein
分子名称: ACETATE ION, Hemolysin, SODIUM ION
著者Morton, C.J, Parker, M.W, Lawrence, S.L, Johnstone, B.A, Tweten, R.K.
登録日2020-06-09
公開日2021-04-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins.
Mbio, 11, 2020
5HHQ
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BU of 5hhq by Molmil
Crystal Structure of HLA-A*0201 in complex with M1-L3W
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
4GET
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BU of 4get by Molmil
Crystal structure of biogenic amine binding protein from Rhodnius prolixus
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Biogenic amine-binding protein
著者Andersen, J.F, Chang, B.W, Xu, X, Mans, B.J, Ribeiro, J.M.
登録日2012-08-02
公開日2013-01-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector of Trypanosoma cruzi.
Acta Crystallogr.,Sect.D, 69, 2013
3GXZ
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BU of 3gxz by Molmil
Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
著者Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
登録日2009-04-03
公開日2009-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
4C0R
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BU of 4c0r by Molmil
Molecular and structural basis of glutathione import in Gram-positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans.
分子名称: CADMIUM ION, CHLORIDE ION, OXIDIZED GLUTATHIONE DISULFIDE, ...
著者Vergauwen, B, Verstraete, K, Senadheera, D.B, Dansercoer, A, Cvitkovitch, D.G, Guedon, E, Savvides, S.N.
登録日2013-08-07
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.547 Å)
主引用文献Molecular and Structural Basis of Glutathione Import in Gram-Positive Bacteria Via Gsht and the Cystine Abc Importer Tcybc of Streptococcus Mutans.
Mol.Microbiol., 89, 2013
8S9P
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BU of 8s9p by Molmil
1:1:1 agrin/LRP4/MuSK complex
分子名称: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
著者Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
登録日2023-03-29
公開日2023-05-17
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
4Z3J
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BU of 4z3j by Molmil
Crystal structure of the lectin domain of PapG from E. coli BI47 in space group P1
分子名称: PapG, lectin domain
著者Jakob, R.P, Navarra, G, Zihlmann, P, Stangier, K, Preston, R.C, Rabbani, S, Maier, T, Ernst, B.
登録日2015-03-31
公開日2016-04-13
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Carbohydrate-Lectin Interactions: An Unexpected Contribution to Affinity.
Chembiochem, 18, 2017
6OSA
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BU of 6osa by Molmil
human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in non-canonical conformation (NC state)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Kato, H.E, Zhang, Y, Kobilka, B.K, Skiniotis, G.
登録日2019-05-01
公開日2019-07-10
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational transitions of a neurotensin receptor 1-Gi1complex.
Nature, 572, 2019
5HEK
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BU of 5hek by Molmil
crystal structure of M1.HpyAVI
分子名称: Adenine specific DNA methyltransferase (DpnA)
著者Ma, B, Zhang, H, Liu, W.
登録日2016-01-06
公開日2016-11-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori
Oncotarget, 7, 2016
4GE1
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BU of 4ge1 by Molmil
Structure of the tryptamine complex of the amine binding protein of Rhodnius prolixus
分子名称: 2-(1H-INDOL-3-YL)ETHANAMINE, Biogenic amine-binding protein, GLYCEROL
著者Andersen, J.F, Chang, B.W, Xu, X, Mans, B.J, Ribeiro, J.M.
登録日2012-08-01
公開日2013-01-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector of Trypanosoma cruzi.
Acta Crystallogr.,Sect.D, 69, 2013
6OOW
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BU of 6oow by Molmil
The crystal structure of 4-ethylbenzoate bound to T252A mutant of CYP199A4
分子名称: 4-ethylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Coleman, T, Bruning, J.B, Bell, S.G.
登録日2019-04-23
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural investigation of the interplay between the substrate and the acid-alcohol pair of residues in cytochrome P450 enzymes
To Be Published
4GIR
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BU of 4gir by Molmil
Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group P41212)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Enolase, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-08-08
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group P41212)
To be Published
163L
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BU of 163l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Blaber, M, Matthews, B.W.
登録日1994-06-20
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
4WFZ
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BU of 4wfz by Molmil
Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase - NaCl Crystal Form
分子名称: RNA-directed RNA polymerase, SODIUM ION
著者Peersen, O.B, McDonald, S.M.
登録日2014-09-17
公開日2014-10-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
5HI1
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BU of 5hi1 by Molmil
Backbone Modifications in the Protein GB1 Helix: Aib24, beta-3-Lys28, beta-3-Lys31, Aib35
分子名称: ACETATE ION, Immunoglobulin G-binding protein G
著者Tavenor, N.A, Reinert, Z.E, Lengyel, G.A, Griffith, B.D, Horne, W.S.
登録日2016-01-11
公開日2016-02-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Comparison of design strategies for alpha-helix backbone modification in a protein tertiary fold.
Chem.Commun.(Camb.), 52, 2016
8HMP
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BU of 8hmp by Molmil
GPR52 with Gs and c17
分子名称: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Chen, B, Xu, F.
登録日2022-12-05
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy.
MedComm (2020), 4, 2023
4WG7
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BU of 4wg7 by Molmil
Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a nano focused beam.
分子名称: CHLORIDE ION, Lysozyme C
著者Coquelle, N, Brewster, A.S, Kappe, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P.
登録日2014-09-18
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams.
Acta Crystallogr.,Sect.D, 71, 2015
156L
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BU of 156l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Blaber, M, Matthews, B.W.
登録日1994-06-20
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995

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