4ICT
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![BU of 4ict by Molmil](/molmil-images/mine/4ict) | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | 分子名称: | (3S,6S)-3-benzyl-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Fonvielle, M, Le Du, M.-H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | 登録日 | 2012-12-11 | 公開日 | 2013-05-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
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8GJH
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![BU of 8gjh by Molmil](/molmil-images/mine/8gjh) | Salmonella ArnA | 分子名称: | Bifunctional polymyxin resistance protein ArnA, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | 著者 | Sousa, M.C, Mitchell, M.E, Gatzeva-Topalova, P.Z. | 登録日 | 2023-03-15 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance. Biochemistry, 62, 2023
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6ZJU
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![BU of 6zju by Molmil](/molmil-images/mine/6zju) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with saccharose | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | 登録日 | 2020-06-29 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 21, 2020
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6ZKA
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![BU of 6zka by Molmil](/molmil-images/mine/6zka) | Membrane domain of open complex I during turnover | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | 著者 | Kampjut, D, Sazanov, L.A. | 登録日 | 2020-06-30 | 公開日 | 2020-10-07 | 最終更新日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | The coupling mechanism of mammalian respiratory complex I. Science, 370, 2020
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4WFF
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![BU of 4wff by Molmil](/molmil-images/mine/4wff) | |
8FAZ
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![BU of 8faz by Molmil](/molmil-images/mine/8faz) | Cryo-EM structure of the human BCDX2 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA repair protein RAD51 homolog 2, DNA repair protein RAD51 homolog 3, ... | 著者 | Jia, L, Wasmuth, E.V, Ruben, E.A, Sung, P, Rawal, Y, Greene, E.C, Meir, A, Olsen, S.K. | 登録日 | 2022-11-29 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural insights into BCDX2 complex function in homologous recombination. Nature, 619, 2023
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6XE7
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![BU of 6xe7 by Molmil](/molmil-images/mine/6xe7) | Carbonmonoxy hemoglobin in complex with the antisickling agent methyl 2-((2-formyl-3-hydroxyphenoxy)methyl)nicotinate | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Pagare, P.P, Safo, M.K, Musayev, F.N. | 登録日 | 2020-06-12 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents. J.Med.Chem., 63, 2020
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1OG2
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![BU of 1og2 by Molmil](/molmil-images/mine/1og2) | Structure of human cytochrome P450 CYP2C9 | 分子名称: | CYTOCHROME P450 2C9, HEME C | 著者 | Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. | 登録日 | 2003-04-23 | 公開日 | 2003-07-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
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5YER
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![BU of 5yer by Molmil](/molmil-images/mine/5yer) | Regulatory domain of HypT from Salmonella typhimurium (Bromide ion-bound) | 分子名称: | BROMIDE ION, Cell density-dependent motility repressor, SULFATE ION | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-19 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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8FIE
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6XQD
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![BU of 6xqd by Molmil](/molmil-images/mine/6xqd) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | 登録日 | 2020-07-09 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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5N5S
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![BU of 5n5s by Molmil](/molmil-images/mine/5n5s) | Crystal structure of aldehyde dehydrogenase 21 (ALDH21) from Physcomitrella patens in complex with NADP+ | 分子名称: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase 21 (ALDH21), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kopecny, D, Vigouroux, A, Briozzo, P, Morera, S. | 登録日 | 2017-02-14 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The ALDH21 gene found in lower plants and some vascular plants codes for a NADP(+) -dependent succinic semialdehyde dehydrogenase. Plant J., 92, 2017
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8FNB
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5D3F
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7FAW
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![BU of 7faw by Molmil](/molmil-images/mine/7faw) | Structure of LW domain from Yeast | 分子名称: | Transcription elongation factor S-II | 著者 | Liao, S, Gao, J, Tu, X. | 登録日 | 2021-07-07 | 公開日 | 2022-07-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.438 Å) | 主引用文献 | Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C. Int.J.Biol.Macromol., 253, 2023
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1FU1
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![BU of 1fu1 by Molmil](/molmil-images/mine/1fu1) | CRYSTAL STRUCTURE OF HUMAN XRCC4 | 分子名称: | ACETIC ACID, DNA REPAIR PROTEIN XRCC4 | 著者 | Junop, M, Modesti, M, Guarne, A, Gellert, M, Yang, W. | 登録日 | 2000-09-13 | 公開日 | 2000-12-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J., 19, 2000
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5N8X
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5N95
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8FIC
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![BU of 8fic by Molmil](/molmil-images/mine/8fic) | Crystal Structure of Erwinia tracheiphila CYP114 in complex with ent-kaurenoic acid (Crystal Form 1) | 分子名称: | (8alpha,9beta,10alpha,13alpha)-kaur-16-en-18-oic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Stewart Jr, C.E, Nagel, R. | 登録日 | 2022-12-16 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis. Proc.Natl.Acad.Sci.USA, 120, 2023
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5D3I
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![BU of 5d3i by Molmil](/molmil-images/mine/5d3i) | Crystal structure of the SSL3-TLR2 complex | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Feitsma, L.J, Huizinga, E.G. | 登録日 | 2015-08-06 | 公開日 | 2015-08-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3). Proc.Natl.Acad.Sci.USA, 112, 2015
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5NC6
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![BU of 5nc6 by Molmil](/molmil-images/mine/5nc6) | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (E)-N-hydroxy-3-(naphthalen-1-yl)prop-2-enamide | 分子名称: | 1,2-ETHANEDIOL, 3-naphthalen-1-yl-~{N}-oxidanyl-propanamide, ACETATE ION, ... | 著者 | Giastas, P, Andreou, A, Balomenou, S, Bouriotis, V, Eliopoulos, E.E. | 登録日 | 2017-03-03 | 公開日 | 2018-02-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors. Biochemistry, 57, 2018
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8RF2
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![BU of 8rf2 by Molmil](/molmil-images/mine/8rf2) | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 1E7 refined against the anomalous diffraction data | 分子名称: | 1-benzothiophen-5-amine, Host translation inhibitor nsp1 | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | 登録日 | 2023-12-12 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms. Acta Crystallogr D Struct Biol, 80, 2024
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8QOI
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![BU of 8qoi by Molmil](/molmil-images/mine/8qoi) | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | 分子名称: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | 著者 | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | 登録日 | 2023-09-29 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | 主引用文献 | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 2024
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6XTW
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![BU of 6xtw by Molmil](/molmil-images/mine/6xtw) | HumRadA33F in complex with peptidic inhibitor 6 | 分子名称: | DNA repair and recombination protein RadA, SULFATE ION, ~{N}-[2-[(2~{S})-2-[[(1~{S})-1-(4-methoxyphenyl)ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxidanylidene-ethyl]quinoline-2-carboxamide | 著者 | Fischer, G, Marsh, M.E, Scott, D.E, Coyne, A.G, Skidmore, J, Abell, C, Hyvonen, M. | 登録日 | 2020-01-16 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death. Cell Chem Biol, 28, 2021
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8FLF
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