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5OF4
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BU of 5of4 by Molmil
The cryo-EM structure of human TFIIH
分子名称: General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4,p52,General transcription factor IIH subunit 4, ...
著者Greber, B.J, Nguyen, T.H.D, Fang, J, Afonine, P.V, Adams, P.D, Nogales, E.
登録日2017-07-10
公開日2017-09-13
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The cryo-electron microscopy structure of human transcription factor IIH.
Nature, 549, 2017
5XM8
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BU of 5xm8 by Molmil
Crystal structure of AsfvPolX in complex with DNA enzyme and Pb.
分子名称: DNA (23-mer), DNA (36-MER), LEAD (II) ION, ...
著者Liu, H.H, Gan, J.H.
登録日2017-05-13
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of an RNA-cleaving DNAzyme.
Nat Commun, 8, 2017
7K9Y
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BU of 7k9y by Molmil
GsI-IIC RT Template-Switching Complex (twinned)
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
著者Stamos, J.L, Lentzsch, A.M.
登録日2020-09-29
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase.
J.Biol.Chem., 297, 2021
8KD7
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BU of 8kd7 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 167bp DNA
分子名称: 167bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
5IVW
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BU of 5ivw by Molmil
Human core TFIIH bound to DNA within the PIC
分子名称: General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4, ...
著者He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E.
登録日2016-03-21
公開日2016-05-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
8TIE
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BU of 8tie by Molmil
Double nuclear outer ring of Nup84-complexes from the yeast NPC
分子名称: NUP133 isoform 1, NUP145 isoform 1, Nucleoporin NUP120, ...
著者Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P.
登録日2023-07-19
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Implications of a multiscale structure of the yeast nuclear pore complex.
Mol.Cell, 83, 2023
5M4S
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BU of 5m4s by Molmil
Transcription factor TFIIA as a single chain protein
分子名称: Transcription initiation factor IIA subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 1
著者Kandiah, E, Gupta, K.
登録日2016-10-19
公開日2017-11-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Elife, 6, 2017
8KD5
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BU of 8kd5 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD6
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BU of 8kd6 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class3
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD3
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BU of 8kd3 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD4
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BU of 8kd4 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD2
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BU of 8kd2 by Molmil
Rpd3S in complex with 187bp nucleosome
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
3IYD
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BU of 3iyd by Molmil
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ...
著者Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L.
登録日2009-08-01
公開日2009-11-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (19.799999 Å)
主引用文献Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Proc.Natl.Acad.Sci.USA, 106, 2009
4USG
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BU of 4usg by Molmil
Crystal structure of PC4 W89Y mutant complex with DNA
分子名称: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
著者Zhao, Y, Liu, J.
登録日2014-07-08
公開日2015-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
Sci.Rep., 5, 2015
7N84
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BU of 7n84 by Molmil
Double nuclear outer ring from the isolated yeast NPC
分子名称: Nucleoporin 145c, Nucleoporin NUP120, Nucleoporin NUP133, ...
著者Akey, C.W, Rout, M.P, Ouch, C, Echevarria, I, Fernandez-Martinez, J, Nudelman, I.
登録日2021-06-13
公開日2022-01-26
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (11.6 Å)
主引用文献Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022
8U3B
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BU of 8u3b by Molmil
Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A
分子名称: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Kompaniiets, D, Wang, D.
登録日2023-09-07
公開日2024-01-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024
5FUR
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BU of 5fur by Molmil
Structure of human TFIID-IIA bound to core promoter DNA
分子名称: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ...
著者Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E.
登録日2016-01-29
公開日2016-04-06
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
1HVU
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BU of 1hvu by Molmil
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT
分子名称: PROTEIN (HIV-1 REVERSE TRANSCRIPTASE), RNA (33 NUCLEOTIDE RNA PSEUDOKNOT)
著者Jaeger, J, Restle, T, Steitz, T.A.
登録日1998-06-30
公開日1999-01-13
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (4.75 Å)
主引用文献The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor.
EMBO J., 17, 1998
6ERQ
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BU of 6erq by Molmil
Structure of the human mitochondrial transcription initiation complex at the HSP promoter
分子名称: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
著者Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
登録日2017-10-18
公開日2017-11-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERP
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BU of 6erp by Molmil
Structure of the human mitochondrial transcription initiation complex at the LSP promoter
分子名称: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
著者Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
登録日2017-10-18
公開日2017-11-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.502 Å)
主引用文献Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
8KB5
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BU of 8kb5 by Molmil
Cryo-EM structure of the human nucleosome containing H3.8
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H.
登録日2023-08-03
公開日2023-10-18
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.26133 Å)
主引用文献Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
8PYR
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BU of 8pyr by Molmil
Crystal structure of the dual T-loop phosphorylated Cdk7/CycH/Mat1 complex
分子名称: 1,2-ETHANEDIOL, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
著者Anand, K, Duster, R, Geyer, M.
登録日2023-07-26
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis of Cdk7 activation by dual T-loop phosphorylation.
Biorxiv, 2024
6T9K
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BU of 6t9k by Molmil
SAGA Core module
分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
著者Wang, H, Cheung, A, Cramer, P.
登録日2019-10-28
公開日2020-01-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the transcription coactivator SAGA.
Nature, 577, 2020
5ZYA
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BU of 5zya by Molmil
SF3b spliceosomal complex bound to E7107
分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ...
著者Finci, L.I, Larsen, N.A.
登録日2018-05-23
公開日2018-06-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action
Genes Dev., 32, 2018
5OQL
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BU of 5oql by Molmil
Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum
分子名称: 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ...
著者Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2017-08-12
公開日2017-10-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017

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件を2024-09-11に公開中

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