PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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1R4F	Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine 分子名称: 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase 著者 Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J. 登録日 2003-10-06 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Leaving group activation by aromatic stacking: an alternative to general Acid catalysis. J.Mol.Biol., 338, 2004
2FQY	PnrA from Treponema pallidum complexed with adenosine. 分子名称: ADENOSINE, Membrane lipoprotein tmpC 著者 Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. 登録日 2006-01-18 公開日 2006-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
4EAR	Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate 分子名称: 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Haapalainen, A.M, Ho, M.C, Suarez, J.J, Almo, S.C, Schramm, V.L. 登録日 2012-03-22 公開日 2013-02-06 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography. Chem.Biol., 20, 2013
8R7N	Overall structure of the U11 snRNP 分子名称: Programmed cell death protein 7, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Zhao, J, Galej, W.P. 登録日 2023-11-26 公開日 2025-02-05 最終更新日 2025-02-19 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of 5' splice site recognition by the minor spliceosome. Mol.Cell, 85, 2025
4ECE	Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with guanine 分子名称: GUANINE, Purine nucleoside phosphorylase 著者 Haapalainen, A.M, Ho, M.C, Suarez, J.J, Almo, S.C, Schramm, V.L. 登録日 2012-03-26 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography. Chem.Biol., 20, 2013
4GKA	Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with phosphate 分子名称: GLYCEROL, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Haapalainen, A.M, Ho, M.C, Suarez, J.J, Almo, S.C, Schramm, V.L. 登録日 2012-08-10 公開日 2013-02-06 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography. Chem.Biol., 20, 2013
2B5J	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481 分子名称: (2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE, MANGANESE (II) ION, Reverse transcriptase P51 SUBUNIT, ... 著者 Himmel, D.H, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Mguyen, C.H, Grierson, D.S, Arnold, E. 登録日 2005-09-28 公開日 2005-12-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
4CMW	Crystal structure of Rv3378c 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Layre, E, Lee, H.J, Young, D.C, Martinot, A.J, Buter, J, Minnaard, A.J, Annand, J.W, Fortune, S.M, Snider, B.B, Matsunaga, I, Rubin, E.J, Alber, T, Moody, D.B. 登録日 2014-01-18 公開日 2014-02-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.209 Å) 主引用文献 Molecular Profiling of Mycobacterium Tuberculosis Identifies Tuberculosinyl Nucleoside Products of the Virulence-Associated Enzyme Rv3378C. Proc.Natl.Acad.Sci.USA, 111, 2014
4LN9	Crystal structure of the dehydratase domain from the terminal module of the rifamycin polyketide synthase 分子名称: Rifamycin polyketide synthase 著者 Gay, D.C, You, Y.-O, Cane, D, Keatinge-Clay, A.T. 登録日 2013-07-11 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structure and stereospecificity of the dehydratase domain from the terminal module of the rifamycin polyketide synthase. Biochemistry, 52, 2013
4LD7	Crystal structure of AnaPT from Neosartorya fischeri 分子名称: Dimethylallyl tryptophan synthase, SODIUM ION, TRIHYDROGEN THIODIPHOSPHATE 著者 Zocher, G, Stehle, T. 登録日 2013-06-24 公開日 2013-12-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases. Chem.Biol., 20, 2013
4CMX	Crystal structure of Rv3378c 分子名称: 1,2-ETHANEDIOL, BENZENE HEXACARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Layre, E, Lee, H.J, Young, D.C, Martinot, A.J, Buter, J, Minnaard, A.J, Annand, J.W, Fortune, S.M, Snider, B.B, Matsunaga, I, Rubin, E.J, Alber, T, Moody, D.B. 登録日 2014-01-18 公開日 2014-02-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Molecular Profiling of Mycobacterium Tuberculosis Identifies Tuberculosinyl Nucleoside Products of the Virulence-Associated Enzyme Rv3378C. Proc.Natl.Acad.Sci.USA, 111, 2014
4DFM	Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in ternary complex with 5-(aminopentinyl)-2-dCTP 分子名称: 1,2-ETHANEDIOL, 5'-d(AAAGCGCGCCGTGGTC)-3', 5'-d(GACCACGGCGC ddG)-3', ... 著者 Bergen, K, Steck, A, Struett, S, Baccaro, A, Welte, W, Diederichs, K, Marx, A. 登録日 2012-01-24 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.886 Å) 主引用文献 Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates. J.Am.Chem.Soc., 134, 2012
2FQX	PnrA from Treponema pallidum complexed with guanosine 分子名称: GUANOSINE, Membrane lipoprotein tmpC 著者 Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. 登録日 2006-01-18 公開日 2006-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
1RT2	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH TNK-651 分子名称: 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL, HIV-1 REVERSE TRANSCRIPTASE 著者 Ren, J, Esnouf, R, Hopkins, A, Willcox, B, Jones, Y, Ross, C, Stammers, D, Stuart, D. 登録日 1996-03-16 公開日 1997-04-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. J.Med.Chem., 39, 1996
2FQW	PnrA from Treponema pallidum as purified from E. coli (bound to inosine) 分子名称: INOSINE, Membrane lipoprotein tmpC 著者 Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. 登録日 2006-01-18 公開日 2006-02-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
1RT1	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH MKC-442 分子名称: 6-BENZYL-1-ETHOXYMETHYL-5-ISOPROPYL URACIL, HIV-1 REVERSE TRANSCRIPTASE 著者 Ren, J, Esnouf, R, Hopkins, A, Willcox, B, Jones, Y, Ross, C, Stammers, D, Stuart, D. 登録日 1996-03-16 公開日 1997-04-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. J.Med.Chem., 39, 1996
2HNZ	Crystal Structure of E138K Mutant HIV-1 Reverse Transcriptase in Complex with PETT-2 分子名称: 1-[2-(4-ETHOXY-3-FLUOROPYRIDIN-2-YL)ETHYL]-3-(5-METHYLPYRIDIN-2-YL)THIOUREA, PHOSPHATE ION, Reverse transcriptase/ribonuclease H 著者 Ren, J, Nichols, C.E, Stamp, A, Chamberlain, P.P, Stammers, D.K. 登録日 2006-07-13 公開日 2006-09-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. Febs J., 273, 2006
7PJ1	Solution structure of isolated Drosophila histone H2A-H2B heterodimer 分子名称: Histone H2A, Histone H2B 著者 van Ingen, H, Zhang, H. 登録日 2021-08-23 公開日 2021-12-08 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Mapping the electrostatic potential of the nucleosome acidic patch. Sci Rep, 11, 2021
6P3M	Tetrahydroprotoberberine N-methyltransferase in complex with S-adenosylhomocysteine 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, tetrahydroprotoberberine N-methyltransferase 著者 Lang, D.E, Morris, J.S, Rowley, M, Torres, M.A, Maksimovich, V.A, Facchini, P.J, Ng, K.K.S. 登録日 2019-05-24 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-function studies of tetrahydroprotoberberineN-methyltransferase reveal the molecular basis of stereoselective substrate recognition. J.Biol.Chem., 294, 2019
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Pena, V. 登録日 2022-01-15 公開日 2023-05-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
6P3N	Tetrahydroprotoberberine N-methyltransferase in complex with S-adenosylmethionine 分子名称: S-ADENOSYLMETHIONINE, tetrahydroprotoberberine N-methyltransferase 著者 Lang, D.E, Morris, J.S, Rowley, M, Torres, M.A, Maksimovich, V.A, Facchini, P.J, Ng, K.K.S. 登録日 2019-05-24 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-function studies of tetrahydroprotoberberineN-methyltransferase reveal the molecular basis of stereoselective substrate recognition. J.Biol.Chem., 294, 2019
6P3O	Tetrahydroprotoberberine N-methyltransferase in complex with (S)-cis-N-methylstylopine and S-adenosylhomocysteine 分子名称: (5S,12bS)-5-methyl-6,7,12b,13-tetrahydro-2H,4H,10H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-5-ium, S-ADENOSYL-L-HOMOCYSTEINE, Tetrahydroprotoberberine N-methyltransferase 著者 Lang, D.E, Morris, J.S, Rowley, M, Torres, M.A, Maksimovich, V.A, Facchini, P.J, Ng, K.K.S. 登録日 2019-05-24 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-function studies of tetrahydroprotoberberineN-methyltransferase reveal the molecular basis of stereoselective substrate recognition. J.Biol.Chem., 294, 2019
6W4V	Structure of anti-ferroportin Fab45D8 分子名称: 1,2-ETHANEDIOL, Fab45D8 Heavy Chain, Fab45D8 Light Chain 著者 Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. 登録日 2020-03-11 公開日 2020-09-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms. Nature, 586, 2020
1UC5	Structure of diol dehydratase complexed with (R)-1,2-propanediol 分子名称: AMMONIUM ION, CYANOCOBALAMIN, POTASSIUM ION, ... 著者 Shibata, N, Nakanishi, Y, Fukuoka, M, Yamanishi, M, Yasuoka, N, Toraya, T. 登録日 2003-04-08 公開日 2003-07-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural rationalization for the lack of stereospecificity in coenzyme B12-dependent diol dehydratase J.Biol.Chem., 278, 2003
1UC4	Structure of diol dehydratase complexed with (S)-1,2-propanediol 分子名称: AMMONIUM ION, CYANOCOBALAMIN, POTASSIUM ION, ... 著者 Shibata, N, Nakanishi, Y, Fukuoka, M, Yamanishi, M, Yasuoka, N, Toraya, T. 登録日 2003-04-08 公開日 2003-07-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural rationalization for the lack of stereospecificity in coenzyme B12-dependent diol dehydratase J.BIOL.CHEM., 278, 2003

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