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3P6U
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BU of 3p6u by Molmil
Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C6-Dans
分子名称: Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B.
登録日2010-10-11
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C6-Dans
To be Published
7VB1
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BU of 7vb1 by Molmil
The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with trans-vaccenic acid
分子名称: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ...
著者Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2021-08-30
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with trans-vaccenic acid
To Be Published
3OLV
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BU of 3olv by Molmil
Structural and functional effects of substitution at position T+1 in CheY: CheYA88V-BeF3-Mg complex
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, MAGNESIUM ION, ...
著者Immormino, R.M, Bourret, R.B.
登録日2010-08-26
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献A Variable Active Site Residue Influences the Kinetics of Response Regulator Phosphorylation and Dephosphorylation.
Biochemistry, 55, 2016
3OLY
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BU of 3oly by Molmil
Structural and functional effects of substitution at position T+1 in CheY: CheYA88M-BeF3-Mn complex
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Immormino, R.M, Bourret, R.B.
登録日2010-08-26
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Variable Active Site Residue Influences the Kinetics of Response Regulator Phosphorylation and Dephosphorylation.
Biochemistry, 55, 2016
2QKB
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BU of 2qkb by Molmil
Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid
分子名称: 1,2-ETHANEDIOL, 5'-D(*DGP*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*DTP*DGP*DTP*DCP*DGP*DCP*DAP*DCP*DTP*DCP*DT)-3', 5'-R(*GP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3'), ...
著者Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W.
登録日2007-07-10
公開日2007-11-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QKK
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Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', ...
著者Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W.
登録日2007-07-11
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
3P7H
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BU of 3p7h by Molmil
Structure of the human Langerin carbohydrate recognition domain in complex with maltose
分子名称: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Skerra, A, Schiefner, A.
登録日2010-10-12
公開日2010-11-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Mol.Immunol., 45, 2008
3OQ7
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BU of 3oq7 by Molmil
Crystal Structures of Multidrug-Resistant Clinical Isolate 769 HIV-1 Protease Variants
分子名称: HIV-1 Protease
著者Yedidi, R.S, Proteasa, G, Martinez-Cajas, J.L, Vickrey, J.F, Martin, P.D, Wawrzak, Z, Kovari, L.C.
登録日2010-09-02
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants.
Acta Crystallogr.,Sect.D, 67, 2011
2QWI
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BU of 2qwi by Molmil
THE X-RAY STRUCTURE OF A COMPLEX OF N-ACETYL-4-GUANIDINO-6-METHYL(PROPYL)CARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-N-acetyl-4-guanidino-6-methyl(propyl) carboxamide-4,5-dihydro-2H-pyran-2-carboxylic acid, CALCIUM ION, ...
著者Varghese, J.N.
登録日1998-04-07
公開日1998-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
Structure, 6, 1998
3OQA
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BU of 3oqa by Molmil
Crystal Structures of Multidrug-Resistant Clinical Isolate 769 HIV-1 Protease Variants
分子名称: HIV-1 Protease
著者Yedidi, R.S, Proteasa, G, Martinez-Cajas, J.L, Vickrey, J.F, Martin, P.D, Wawrzak, Z, Kovari, L.C.
登録日2010-09-02
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants.
Acta Crystallogr.,Sect.D, 67, 2011
2QXL
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BU of 2qxl by Molmil
Crystal Structure Analysis of Sse1, a yeast Hsp110
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein homolog SSE1, MAGNESIUM ION, ...
著者Hendrickson, W.A, Liu, Q.
登録日2007-08-12
公開日2007-10-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1.
Cell(Cambridge,Mass.), 131, 2007
3OSH
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BU of 3osh by Molmil
Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution
分子名称: (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, CALCIUM ION, Phospholipase A2 isoform 3
著者Shukla, P.K, Kaushik, S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2010-09-09
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution
To be Published
3OU1
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BU of 3ou1 by Molmil
MDR769 HIV-1 protease complexed with RH/IN hepta-peptide
分子名称: MDR HIV-1 protease, RH/IN substrate peptide
著者Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Kovari, L.C.
登録日2010-09-14
公開日2011-03-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease.
Protein J., 30, 2011
2QW9
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BU of 2qw9 by Molmil
Crystal structure of bovine hsc70 (1-394aa)in the apo state
分子名称: GLYCEROL, Heat shock cognate 71 kDa protein
著者Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R.
登録日2007-08-10
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
7VDN
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BU of 7vdn by Molmil
High resolution crystal structure of Sperm Whale Myoglobin in the carbonmonoxy form
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Shibayama, N, Sato-Tomita, A, Ishimoto, N, Park, S.Y.
登録日2021-09-07
公開日2022-09-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献X-ray fluorescence holography of biological metal sites: Application to myoglobin.
Biochem.Biophys.Res.Commun., 635, 2022
2QXI
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BU of 2qxi by Molmil
High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone
分子名称: Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
著者Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P.
登録日2007-08-11
公開日2008-01-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3P5F
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BU of 3p5f by Molmil
Structure of the carbohydrate-recognition domain of human Langerin with man2 (Man alpha1-2 Man)
分子名称: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose, ...
著者Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I.
登録日2010-10-08
公開日2010-12-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7501 Å)
主引用文献Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site.
J.Mol.Biol., 405, 2011
2QCA
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BU of 2qca by Molmil
A New Crystal Form of Bovine Pancreatic RNase A in Complex with 2'-Deoxyguanosine-5'-monophosphate
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Ribonuclease pancreatic
著者Larson, S.B, Day, J.S, Cudney, R, McPherson, A, Center for High-Throughput Structural Biology (CHTSB)
登録日2007-06-19
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.
Acta Crystallogr.,Sect.F, 63, 2007
3P6V
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BU of 3p6v by Molmil
Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog 3Et-AdaC1-Etg-Boc
分子名称: Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B.
登録日2010-10-11
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog 3Et-AdaC1-Etg-Boc
To be Published
3OY5
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The crystal structure of uPA complex with peptide inhibitor MH027 at pH7.4
分子名称: MH027, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-22
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
2QD7
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HIV-1 Protease Mutant V82A with potent Antiviral inhibitor GRL-98065
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T.
登録日2007-06-20
公開日2008-04-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease.
J.Med.Chem., 50, 2007
2QFH
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Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H.
分子名称: Complement factor H
著者Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J.
登録日2007-06-27
公開日2007-09-25
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
2QIU
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Structure of Human Arg-Insulin
分子名称: Insulin, ZINC ION
著者Sreekanth, R, Pattabhi, V, Rajan, S.S.
登録日2007-07-05
公開日2008-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural interpretation of reduced insulin activity as seen in the crystal structure of human Arg-insulin
Biochimie, 90, 2008
2QZD
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BU of 2qzd by Molmil
Fitted structure of SCR4 of DAF into cryoEM density
分子名称: Complement decay-accelerating factor
著者Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G.
登録日2007-08-16
公開日2007-10-30
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (14 Å)
主引用文献Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
2QZK
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Crystal structure of human Beta Secretase complexed with I21
分子名称: 2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile, Beta-secretase 1
著者Munshi, S.
登録日2007-08-16
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007

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