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5LWH
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CeuE (Y288F variant) a periplasmic protein from Campylobacter jejuni.
分子名称: Enterochelin ABC transporter substrate-binding protein, ZINC ION
著者Wilde, E.J, Blagova, E, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J, Duhme-Klair, A.-K, Wilson, K.S.
登録日2016-09-16
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
5LXB
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Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with palonosetron
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Soluble acetylcholine receptor, palonosetron
著者Ulens, C.
登録日2016-09-20
公開日2016-10-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Palonosetron-5-HT3 Receptor Interactions As Shown by a Binding Protein Cocrystal Structure.
ACS Chem Neurosci, 7, 2016
5LZD
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Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
1FMO
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CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE
分子名称: ADENOSINE, CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN
著者Narayana, N, Cox, S, Shaltiel, S, Taylor, S.S, Xuong, N.-H.
登録日1997-07-08
公開日1998-01-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
Biochemistry, 36, 1997
5LZT
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BU of 5lzt by Molmil
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
8TCE
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BU of 8tce by Molmil
Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3353871
分子名称: (2S)-3-phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic acid, Apolipoprotein(a)
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-06-30
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
5M36
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The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ...
著者Bier, D, Ottmann, C.
登録日2016-10-14
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
5M3K
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BU of 5m3k by Molmil
A multi-component acyltransferase PhlABC from Pseudomonas protegens
分子名称: 2,4-diacetylphloroglucinol biosynthesis protein PhlB, 2,4-diacetylphloroglucinol biosynthesis protein PhlC, PhlA, ...
著者Pavkov-Keller, T, Schmidt, N.G, Kroutil, W, Gruber, K.
登録日2016-10-15
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structure and Catalytic Mechanism of a Bacterial Friedel-Crafts Acylase.
Chembiochem, 20, 2019
7TV4
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BU of 7tv4 by Molmil
Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin
分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Polyubiquitin-C, ...
著者Rahighi, S, Iyer, M, Oveisi, H.
登録日2022-02-03
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain.
Sci Rep, 12, 2022
6G1E
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BEAT Fc with improved heterodimerization (Q3A-D84.4Q)
分子名称: Immunoglobulin gamma-1 heavy chain, Immunoglobulin heavy constant gamma 1,Immunoglobulin heavy constant gamma 3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stutz, C, Blein, S.
登録日2018-03-21
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献A single mutation increases heavy chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species.
J.Biol.Chem., 2020
6G20
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BU of 6g20 by Molmil
Crystal structure of a fluorescence optimized bathy phytochrome PAiRFP2 derived from wild-type Agp2 in its functional Meta-F intermediate state.
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, ...
著者Schmidt, A, Sauthof, L, Szczepek, M, Scheerer, P.
登録日2018-03-22
公開日2018-11-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural snapshot of a bacterial phytochrome in its functional intermediate state.
Nat Commun, 9, 2018
6JRE
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BU of 6jre by Molmil
Structure of N-terminal domain of Plasmodium vivax p43 (PfNTD) solved by Co-SAD phasing
分子名称: Aminoacyl-tRNA synthetase-interacting multifunctional protein p43, COBALT (II) ION
著者Manickam, Y, Harlos, K, Sharma, M, Gupta, S, Sharma, A.
登録日2019-04-03
公開日2020-03-11
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.
Acta Crystallogr D Struct Biol, 76, 2020
7THN
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BU of 7thn by Molmil
Crystal structure of PigI trapped with PigG using a proline adenosine vinylsulfonamide inhibitor
分子名称: 5'-deoxy-5'-({(2S)-2-({2-[(N-{(2R)-4-[(dioxo-lambda~5~-phosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-2-[(2S)-pyrrolidin-2-yl]ethanesulfonyl}amino)adenosine, AZIDE ION, GLYCEROL, ...
著者Corpuz, J.C, Podust, L.M.
登録日2022-01-11
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Essential Role of Loop Dynamics in Type II NRPS Biomolecular Recognition.
Acs Chem.Biol., 17, 2022
6J5X
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BU of 6j5x by Molmil
Crystal structure of fumarylpyruvate hydrolase from Corynebacterium glutamicum in complex with Mn2+ and pyruvate
分子名称: MANGANESE (II) ION, PYRUVIC ACID, Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase, ...
著者Hong, H, Seo, H, Kim, K.-J, Park, W.
登録日2019-01-12
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Sequence, structure and function-based classification of the broadly conserved FAH superfamily reveals two distinct fumarylpyruvate hydrolase subfamilies.
Environ.Microbiol., 22, 2020
6JQS
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BU of 6jqs by Molmil
Structure of Transcription factor, GerE
分子名称: DNA-binding response regulator
著者Lee, J.H, Lee, C.W.
登録日2019-04-01
公開日2019-04-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of a transcription factor, GerE (PaGerE), from spore-forming bacterium Paenisporosarcina sp. TG-14.
Biochem.Biophys.Res.Commun., 513, 2019
6J8V
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BU of 6j8v by Molmil
Structure of MOEN5-SSO7D fusion protein in complex with ligand 2
分子名称: FARNESYL, MoeN5,DNA-binding protein 7d
著者Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T.
登録日2019-01-21
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
Biochem. Biophys. Res. Commun., 511, 2019
7U91
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Crystal structure of queuine salvage enzyme DUF2419, in complex with queuosine-5'-monophosphate
分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-7-(5-O-phosphono-beta-D-ribofuranosyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Hung, S.-H, Swairjo, M.A.
登録日2022-03-09
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.
Nucleic Acids Res., 51, 2023
5MW1
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cryoEM structure of crenactin double helical filament at 3.8A resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin/actin family protein
著者Izore, T, Lowe, J.
登録日2017-01-17
公開日2017-02-08
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Crenactin forms actin-like double helical filaments regulated by arcadin-2.
Elife, 5, 2016
7U07
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Crystal structure of queuine salvage enzyme DUF2419, apo form
分子名称: Queuine salvage enzyme DUF2419
著者Hung, S.-H, Swairjo, M.A.
登録日2022-02-17
公開日2022-12-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.
Nucleic Acids Res., 51, 2023
7TUX
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BU of 7tux by Molmil
Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Hypoxanthine-guanine-xanthine phosphoribosyltransferase, ...
著者Harijan, R.K, Minnow, Y.V.T, Bonanno, J.B, Almo, S.C, Schramm, V.L.
登録日2022-02-03
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase.
Acs Chem.Biol., 17, 2022
6G6U
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BU of 6g6u by Molmil
The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 2.7 Angstrom resolution
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, NITRATE ION, Voltage-dependent anion-selective channel protein 1
著者Razeto, A, Gribbon, P, Loew, C.
登録日2018-04-03
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献The dynamic nature of the VDAC1 channels in bilayers as revealed by two crystal structures of the human isoform in bicelles at 2.7 and 3.3 Angstrom resolution: implications for VDAC1 voltage-dependent mechanism and for its oligomerization
To Be Published
5M63
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Crystal structure of group B Streptococcus type III DP2 oligosaccharide bound to Fab NVS-1-19-5
分子名称: (2~{R},3~{R},4~{S},5~{S})-2-[bis(oxidanyl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, H chain of Fab NVS-1-19-5, ...
著者Carboni, F, Adamo, R, Veggi, D, Rappuoli, R, Malito, E, Margarit, I.R, Berti, F.
登録日2016-10-24
公開日2017-05-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1FFP
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CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33 (C9M/K1S)
分子名称: BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ...
著者Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
登録日2000-07-25
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
1FG5
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CRYSTAL STRUCTURE OF BOVINE ALPHA-1,3-GALACTOSYLTRANSFERASE CATALYTIC DOMAIN.
分子名称: N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE
著者Gastinel, L.N, Bignon, C, Shaper, J.H, Joziasse, D.H.
登録日2000-07-28
公開日2001-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bovine alpha1,3-galactosyltransferase catalytic domain structure and its relationship with ABO histo-blood group and glycosphingolipid glycosyltransferases.
EMBO J., 20, 2001
7U1O
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Crystal structure of queuine salvage enzyme DUF2419 complexed with queuosine
分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-7-beta-D-ribofuranosyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, DI(HYDROXYETHYL)ETHER, MALONATE ION, ...
著者Hung, S.-H, Swairjo, M.A.
登録日2022-02-21
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.
Nucleic Acids Res., 51, 2023

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