5LXB

Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with palonosetron

Summary for 5LXB

Entry DOI	10.2210/pdb5lxb/pdb
Descriptor	Soluble acetylcholine receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, palonosetron, ... (4 entities in total)
Functional Keywords	cys-loop receptor, 5-ht3 receptor, acetylcholine binding protein
Biological source	Aplysia californica (California sea hare)
Total number of polymer chains	10
Total formula weight	279114.00
Authors	Ulens, C. (deposition date: 2016-09-20, release date: 2016-10-12, Last modification date: 2024-01-17)
Primary citation	Price, K.L.,Lillestol, R.K.,Ulens, C.,Lummis, S.C. Palonosetron-5-HT3 Receptor Interactions As Shown by a Binding Protein Cocrystal Structure. ACS Chem Neurosci, 7:1641-1646, 2016 Cited by PubMed: 27656911 DOI: 10.1021/acschemneuro.6b00132 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.34 Å)

Structure validation